A Tale of Three Metals and The Fate of Western Civilization

A Tale of Three Metals and The Fate of Western Civilization



The Romans drank beverages prepared in lead vessels, and brought spring water into their homes through lead pipes. Lead poisoning undoubtedly hastened the fall of the Roman empire. So when we think about the evidence that we are harming ourselves, and our children, with lead in the water, mercury in the air, mercury in flu vaccines, and aluminum in many other vaccines, one has to wonder: what are the likely effects on society?

  1. African Americans will suffer the most. Due to Vitamin D deficiency, African Americans at northern latitudes can be expected to be most sensitive to toxins because they rely on dietary Vitamin D to drive their cellular detoxification systems. The fix? Measure blood Vitamin D levels, and absent any mutation that would preclude increased doses of Vitamin D, improve brain health via addition Vitamin D supplementation.
  2. Young adults (millenials) will have different sociality, and higher rates of early-age psychological disorders such as schizophrenia. They may also experience higher rates of early age of onset Parkison’s disease, Alzheimer’s disease, and other neurodegenerative diseases. The fix? Filter aluminum out of the water, try silica-rich mineral waters, silica drops, with a preference for sources with the more biologically available silicic acid. In short, detoxify their food, water, and everything in their environment, and more (see below).
  3. Young children with special education needs will tend to be more violent and brain studies will show increased presence of amyloid precursor protein, the kind responsible for Alzheimer’s disease.
  4. There will be a population-wide downward shift in IQ.
  5. There will be a plague of multiple chemical sensitivity.
  6. Academics will be stretched thin and the curriculum dumbed down to the point where schools will have to stop giving grades. When 20% of the class can no longer function academically to take and exam, the rest will be asked to “help” their classmates learn.
  7. Families will become increasingly stressful social units. Divorce rates will skyrocket.
  8. People will become increasingly dependent on the State (Nanny State).
  9. Those most able to withstand the toxic effects of accumulating neurotoxins will become increasingly taxed because their income and property will have to sustain an increasingly demanding medico-government empire.
  10. When they, too, begin to fall apart, the tax base will falter.
  11. Violence will become increasingly common. Those most damaged will tend to kill and injure those who are capable.
  12. America will tear itself apart from within.

This doomsday scenario is not inevitable. So what can we do to prevent this?

  1. Listen to the mothers. They have experience in what works. NIH has avoided real research on neurodevelopment disorders that address neurotoxic metal exposure since the CDC worked so hard to defraud the public on the vaccine/autism link. They gambled, lost, and we now pay the cost.
  2. These solutions must be tested in combinations in clinical studies to insure safety, and also to validate them (if they do help). They must be studied NOW, before it’s too late.

Option 1. Environmental Detoxification. Remove all neotoxins from your home. Use reverse osmosis water filters, and use filtered water for everything – even cooking – because aluminum is used to condition the water coming from the tap. Fluoride is another issue, and your filtration should also remove fluoride. Eat organic foods and nothing out of aluminum containers. Certainly never cook in aluminum pots.

Option 2. Get the Aluminum Out. Consider using high silicic acid mineral water, or adding silicic acid drops to your filtered water to bind any aluminum from food. Other possibilities include malic acid, magnesium, and acetoacetic acid:

Principles of Orthomolecularism. R.A.S. Hemat: “Aluminum can be effectively complexed and excreted with silicon, a complex of malic acid and mg, and acetoacetic acid.”

Precise combinations that work best and are safe are not yet determined. That’s why we need studies.

Doctor Toni Bark, MD informs me that ketogenic diet can also help reduce brain inflammation and reduce the effects of toxic metals from the body and the brain – including the reduction of brain amyloid. And Dr. Richard Frey’s research on intranasal insulin and intranasal deferoxamine seems very promising for the actual removal of iron and aluminum from the brain. Care should be taken to conduct any such research under the direct care of a physician.

Option 3. Up the Vitamin D3, watch the A, Avoid Folic Acid. Dr. Keith Baggerly, MD, has determined that the FDA flubbed in it recommended daily Vit D intake. As a result, most Americans are Vit D deficient. Increased Vitamin D3 can be expected to improve many aspects of health by helping our cells properly fold proteins. Vits A and D are antagonistic, and so watch all sources of Vit A and make sure you and your child are not taking in too much Vitamin A. Read The Big Vitamin D Mistake. and Grant Genereux’s resources on Vit A toxicity [1] [2].

Much of our population has MTHFR mutations that cause problems with Folic Acid. Moms taking prenatal vitamins should seek methyl folate or folinic acid instead of folic acid. Children’s vitamins with methyl folate are also available.

Option 5. Reduce Brain Inflammation. Chronic low-grade inflammation is a hallmark of autism. Powerful brain antioxidants include N-acetylcysteine and glutathione. It seems likely that everyone with a brain could benefit from less brain inflammation.

Option 6. Improve the Gut. The commensal (helpful) bacteria in the large intestine can become significantly altered after antibiotic use to treat ear infections, most likely caused by harm from to the immune system from thimerosal. Pro-biotics may help, as will eating organic.

Option 7. Keep This Handy for Bad Head Days. Brain dysfunction from metal-induce excitotoxicity involves high glutmate levels in the brain. Oxaloacetate can reduce blood glutamate levels, allowing the excess glutamate in the brain to spill into the blood. Oxaloacetate is used after stroke to reduce the exitotoxic brain injury. Research is needed to determine if it should be used after vaccination to reduce the incidence of vaccine-induced excitotoxicity. And aluminum should be removed from vaccines because the schedule results in toxic doses in infants.

Option 8. HBOT is HOT. Consider Hyperbaric Oxygen Therapy (HBOT). HBOT can increase de novo neurogenesis. If the brain has suffered a loss of neurons due to toxic exposure, increased neurogenesis – at the right time in development – could ultimately be shown to increase IQ.

Option 9. Avoid Thimerosal. If you choose to use a flu vaccination, ask the doctor for the type of flu shot that does not contain thimerosal.

Option 10. Tell Congress You Want Research Reform.

No studies of the synergistic toxicity of aluminum, lead and mercury have been conducted at doses reflecting the vaccine schedule and daily exposure due to leaching of lead from pipes into homes.

We know which homes have lead pipes. Departments of Health should consider telling parents of children in those homes to avoid exposures to mercury and to aluminum – in other words, to skip vaccines that contain these neurotoxic metals. The children will become more educated, better behaved, make better decisions, commit fewer crimes, and overall have better lives. Toxicity of lead, aluminum and mercury is synergistic.

No studies of the options and combinations of options listed above have been conducted to determine if we could improve overall brain health in children and adults. This research is badly needed. YOU can make it happen.

Make an appointment with your Congressional Representative and ask them to create the Brain Health 2030 initiative designed to reverse the ill effects of the past 30 years of industry and medicine on brains, and on our childrens’ brains. These interventions are not intrusive. Studies could be done also with the Department of Education to determine whether reports of violence decrease, grades increase, drop-out rates decrease if entire SCHOOLS – including administrators – are enrolled in Healthy Brain programs, which could incorporate aspects of mindfulness.

You can join the Neurodevelopment Research Reform group on Facebook where ideas on the Brain Health 2030 initiative are shared. And you can support our efforts to compile the most promising evidence-based approaches to improving brain health by supporting IPAK’s Neurodevelopment Research Reform Initiative.

This article is a call for research reform. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Check with your physician before changing any mode of medical treatment for your child, or yourself.

Further Reading:

Lyons-Weiler, J and R. Ricketson. 2018. Reconsideration of the Immunotherapeutic Pediatric Safe Dose Levels of Aluminum. Journal and Trace Elements in Medicine and Biology 48:67 73.


Thanks to Tim Lundeen for the Vit A information and of course to the outstanding medical doctor, Dr. Toni Bark, MD for permission to cite her expertise.

Neuroimmune Toxicity of Aluminum Adjuvants 1: Safety studies of aluminum in vaccines lack immunotoxicity analysis of this immunological adjuvant: Ignorance or deception? -Vinu Arumugham

This article is part of a series of guest articles to jameslyonsweiler.com on the neurological and immunological toxicity of aluminum-containing adjuvants in vaccines.  These articles appear by invitation to the authors.  -JLW

The safety studies most often referred by vaccine regulators when making claims about the safety of aluminum in vaccines, have ignored the immunotoxicity of aluminum.

Vaccinologists admit that they neither understand the general immunological mechanisms involved in vaccination nor do they understand the mechanisms involved in aluminum adjuvant action.

Thus vaccine regulators have no scientific basis to make vaccine safety claims. Given this situation one would expect that vaccine regulators would be very cautious about making vaccine safety claims. Instead, they collude with vaccine makers to actively hide vaccine safety problems and mislead the public.

The dual role of immunotoxicity and neurotoxicity of aluminum in autism is also covered. Cow’s milk contaminated aluminum adjuvanted vaccines cause the synthesis of folate receptor antibodies. These antibodies block folate uptake causing cerebral folate deficiency and autism. The folate deficiency in turn, causes aluminum accumulation in the brain, resulting in neurotoxicity and exacerbation of autism.


Vaccine safety authorities such as the US Food and Drug Administration (FDA) and the Australian National Centre for Immunisation Research & Surveillance (NCIRS) use studies such as Mitkus et al. 1 and Jefferson et al.2 to claim that aluminum adjuvants in vaccines are safe.


Mitkus et al.1 provide the following description of the effect of aluminum adjuvants on the immune system:

“Aluminum adjuvant are important components of vaccines, since they stimulate the immune system to respond more effectively to protein or polysaccharide antigens that have been adsorbed to the surface of insoluble aluminum particles. Specifically, these coated particles are phagocytized by cells of the innate immune system (e.g., macrophages) and activate intracytoplasmic sensors of pathogen-associated molecular patterns located within the cells, such as the nucleotide-binding domain leucine-rich repeat-containing family of sensors ([6]; Schroder and Tschopp [30]). The functional consequence of activation of this intracellular system is the activation of certain enzymatic caspases that cleave pro-interleukin (IL)-1β to interleukin (IL)-1β. The secretion of the mature cytokine, IL-1β, leads to an inflammatory reaction and a downstream Th2-dependent antibody response [7], which amplify the immune response to the antigen. Adjuvanted aluminum, therefore, plays a vital role in facilitating the response that underlies the immunoprotection afforded by vaccines.”


The rest of the Mitkus et al. review focuses on body burden of aluminum after it is absorbed from the muscle into the blood. They completely ignored any negative immunological effects that aluminum can have while it is still in the muscle (following intramuscular vaccine administration).

The quoted paragraph above assumes that the only proteins in the vaccine are viral/bacterial target proteins required for immunoprotection. In that case, as they state, the stimulation by aluminum plays a vital role in generating immunoprotection.

But obviously, vaccines contain numerous other proteins including food proteins (ovalbumin, milk, soy, yeast, oils from sesame, peanut, fish etc.)3,4, culture medium cell proteins (Vero monkey kidney cell proteins, calf serum proteins, WI38/MRC5 fibroblast cell proteins, chick embryo cell culture proteins etc.)3, non-target viral/bacterial proteins5, that are also adsorbed on to the surface of insoluble aluminum particles. As they state then, aluminum adjuvants stimulate the immune system to respond more effectively to ALL these proteins as well. The result is off-target immune responses that includes synthesis of antibodies against any and all of these proteins as well as cell-mediated immune responses.

The result of such a response of course includes food allergy6-9, asthma10, autism11,12 and autoimmune diseases13,14.

How can they perform a safety assessment of aluminum in vaccines while completely ignoring this immunological effect?

Jefferson et al.2 reviewed eight studies (listed in Table 2 of Jefferson et al.) on the effect of aluminum adjuvants. Any vaccine will need about 3-4 weeks to take effect. That’s how long it takes for the immune system to develop the appropriate immune response and antibodies. For this reason, vaccine effectiveness investigators wait at least one month post vaccination to assess effectiveness.15

Aluminum compounds are of course an immunological adjuvant in vaccines.16. So their immunological effect (positive or negative) can only be assessed if the follow-up period is greater than 4 weeks. However, only two out of eight studies in Jefferson et al. had a follow up period of >4 weeks. So rest of the studies they included were useless to assess immunological safety of aluminum adjuvants. Even those two studies ignored immune disorders such as allergies, asthma, autism or autoimmunity. As previously described, each of these immune disorders can be initiated by IgE mediated allergy11 or the Th2 response, which aluminum adjuvants are known to produce.1,17

So not only were the original studies flawed, Jefferson et al. made the mistake of including these flawed studies in their analysis. To really evaluate the safety of aluminum salts in vaccines, one would have to account for all known/potential immunological mechanisms involved with aluminum adjuvants. What are the potential negative outcomes due to that mechanism? What tests are needed to check for those outcomes? Would the outcomes be overt disease or will they be sub-clinical effects for years? This would determine follow-up times and decision on serological examination. For example: to assess if aluminum may be increasing the risk of sensitization to cow’s milk proteins contaminating the vaccine, one would not only have to wait for 4 weeks after vaccination, but also challenge the patient with cow’s milk, pre- and post- vaccination, to assess the impact. Similarly, to check if aluminum induced an autoimmune disease that may only show up years later, one would have to perform autoimmune serology pre- and post-vaccination checking for changes in autoantibody levels, as suggested by Wraith et al.18

These studies have never been performed. Why?  In fact, vaccine makers seem to go out of the way to obscure the adverse effects of aluminum adjuvants by injecting aluminum adjuvant into control subjects during vaccine clinical safety trials.15

Given this situation, the Jefferson et al. conclusion: “Despite a lack of good-quality evidence we do not recommend that any further research on this topic is undertaken.” is inexplicable, and raises serious questions about the manner in which vaccine safety investigations are conducted.

Evidence of aluminum adjuvant dangers

Morris et al.19 have called for the elimination of aluminum adjuvant in vaccines. Prof. Franco Celada, Dept. of Pathology, NYU School of Medicine, called for safety studies of aluminum adjuvant induced innate immune system activation (personal email communication, Oct 2017) in the context of low affinity self reactive (LASR) T cell mediated autoimmune diseases13,14 caused by animal protein contaminated vaccines.

Anders et al.20 have called for the re-evaluation of aluminum adjuvants in vaccines due to its role in boosting IgE mediated responses. In other words, a Th2-dependent antibody response as described by Mitkus et al.1 and Terhune et al.21 Terhune et al.22 further link Treg dysregulation in atopic disease to aluminum adjuvants.  Shoenfeld et al.23 describe aluminum adjuvant-induced autoimmunity.

Aluminum immunotoxicity followed by neurotoxicity in autism

Many vaccines contain casein or casamino acids of bovine milk origin and are thus contaminated with all bovine milk proteins.3,24 One such protein is the bovine folate receptor (FR) protein25. Such aluminum-adjuvanted, bovine FR protein contaminated vaccines can cause IgE mediated sensitization to the FR protein (aluminum adjuvant induced Th2 response1).4,6,10

Since FR concentration in bovine milk is low, the patient can still consume bovine milk without developing an allergic reaction.25,26 It has been shown that consuming milk when sensitized (via an oral immunotherapy protocol, for example) will result in the synthesis of IgG4 antibodies specific to milk proteins.8

In this case, bovine milk consumption causes FR specific IgG4 synthesis. These IgG4 antibodies cross-react with human folate receptors. Human and bovine FR proteins have 90% amino acid sequence homology.27  IgG4 specific to FR is the main antibody involved in binding/blocking folate receptors in the choroid plexus, blocking folate uptake to the brain.27

This results in cerebral folate deficiency and autism.28 Folate deficiency in turn, results in aluminum accumulation in the brain and aluminum-induced neurotoxicity.29-31

The source of the aluminum could of course be the diet, pollutant inhalation and aluminum-adjuvanted vaccines. Mold et al.32 have demonstrated such aluminum accumulation in human autistic brain tissue.


The FDA makes a mockery of science by comparing aluminum in vaccines to dietary aluminum.33 In that case, we should be drinking our aluminum adjuvanted vaccines, instead of intramuscular injection. The FDA’s Mitkus et al. study1 is entitled “Updated aluminum pharmacokinetics following infant exposures through diet and vaccination.”. They studied pharmacokinetics – how aluminum moves through the body. While aluminum pharmacokinetics related safety needs to be understood, they cannot ignore aluminum adjuvant immunotoxicity, if they were really interested in vaccine aluminum adjuvant safety. If the FDA is incapable of even determining the appropriate lines of safety investigations required, how can they be in charge of vaccine safety? How can we expect vaccines approved by the FDA to be safe?

Safety needs engineering not tinkering

For decades, vaccinologists have been reluctant to understand the immunological mechanism of how vaccines work, fail or hurt the body.

Pulendran et al.37 wrote:

“Despite their success, one of the great ironies of vaccinology is that the vast majority of vaccines have been developed empirically, with little or no understanding of the immunological mechanisms by which they induce protective immunity. However, the failure to develop vaccines against global pandemics such as infection with human immunodeficiency virus (HIV) despite decades of effort has underscored the need to understand the immunological mechanisms by which vaccines confer protective immunity.”

Mojsilovic16: “Some of the first adjuvants discovered back then, on empirical basis of trial and error, are still in widespread use today, but only recently some light on the molecular mechanisms of their action has been shed.”

There seems to be little interest among vaccine developers and regulators in understanding the mechanisms of immunoprotection or immunotoxicity of vaccines and adjuvants. This is no way to build a safety critical product, centuries after its invention.

Since the immunological mechanisms of vaccines are not understood, one would expect that vaccine makers and regulators will be extremely cautious about making vaccine safety claims. One would expect that they will thoroughly investigate even the slightest indication of vaccine-induced adverse events.

Instead, we find vaccine makers and regulators collude to hide vaccine safety problems. The ShingrixTM vaccine was recently approved after an inadequate safety evaluation.35 The FDA briefing document (Sep 2017) describes serious adverse events (SAEs) including supraventricular tachycardia following Shingrix vaccination in clinical studies. The Shingrix vaccine package insert (revised 10/2017)36 has no reference to supraventricular tachycardia at all.


Elizabeth Hart, Adelaide, South Australia, suggested this review and provided background material.


1. Mitkus RJ, King DB, Hess MA, Forshee RA, Walderhaug MO. Updated aluminum pharmacokinetics following infant exposures through diet and vaccination. Vaccine. 2011 Nov 28;29(51):9538–43.

2. Jefferson T, Rudin M, Di Pietrantonj C. Adverse events after immunisation with aluminium-containing DTP vaccines: systematic review of the evidence. Lancet Infect Dis. United States; 2004 Feb;4(2):84–90.

3. Vaccine Excipient & Media Summary [Internet]. 2015 [cited 2016 Jan 16]. Available from: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf

4. Arumugham V. Professional Misconduct by NAM Committee on Food Allergy [Internet]. 2016. Available from: https://www.zenodo.org/record/1034559

5. Ahmed SS, Volkmuth W, Duca J, Corti L, Pallaoro M, Pezzicoli A, et al. Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2 (ABSTRACT ONLY). Sci Transl Med. 2015;7(294):294ra105–294ra105.

6. Arumugham V. Evidence that Food Proteins in Vaccines Cause the Development of Food Allergies and Its Implications for Vaccine Policy. J Dev Drugs. 2015;4(137):2.

7. Platts-Mills TAE. The allergy epidemics: 1870-2010. Journal of Allergy and Clinical Immunology. 2015. p. 3–13.

8. Hoyt AEW, Schuyler AJ, Heymann PW, Platts-Mills TAE, Commins SP. Alum-Containing Vaccines Increase Total and Food Allergen-Specific IgE, and Cow’s Milk Oral Desensitization Increases Bosd4 IgG4 While Peanut Avoidance Increases Arah2 IgE: The Complexity of Today’s Child with Food Allergy. J Allergy Clin Immunol. Elsevier; 2017 Jul 7;137(2):AB151.

 9. Alice Hoyt, Peter Heymann, Alexander Schuyler, Scott Commins TAEP-M. Changes in IgE Levels Following One-Year Immunizations in Two Children with Food Allergy [Internet]. 2015. Available from: https://wao.confex.com/wao/2015symp/webprogram/Paper9336.html

10. Arumugham V. Medical muddles that maim our children with allergies, asthma and autism [Internet]. Unpublished; 2017. Available from: https://www.zenodo.org/record/1034595

11. Arumugham V. Autism Spectrum Disorders: A special case of vaccine-induced cow’s milk allergy? [Internet]. 2017. Available from: https://www.zenodo.org/record/1034557

12. Arumugham V. Strong protein sequence alignment between autoantigens involved in maternal autoantibody related autism and vaccine antigens [Internet]. 2017. Available from: https://www.zenodo.org/record/1034571

13. Arumugham V. Cancer immunology, bioinformatics and chemokine evidence link vaccines contaminated with animal proteins to autoimmune disease: a detailed look at Crohn’s disease and Vitiligo [Internet]. 2017. Available from: https://www.zenodo.org/record/1034777

14. Arumugham V. Bioinformatics analysis links type 1 diabetes to vaccines contaminated with animal proteins and autoreactive T cells express skin homing receptors consistent with injected vaccines as causal agent [Internet]. 2017. Available from: https://www.zenodo.org/record/1034775

15. Gardasil Package Insert [Internet]. Available from:


16. Mojsilovic SB. Immunological effects of adjuvants, their mechanisms, and relevance to vaccine safety. Cent Eur J Paediatr Vol 13, No 1 Cent Eur J Paediatr. 2017;

17. Lindblad EB. Aluminium compounds for use in vaccines. Immunology and Cell Biology. 2004. p. 497–505.

18. Wraith DC, Goldman M, Lambert P-H. Vaccination and autoimmune disease: what is the evidence? Lancet (London, England). England; 2003 Nov;362(9396):1659–66.

19. Morris G, Puri BK, Frye RE. The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved? Metab Brain Dis. United States; 2017 Oct;32(5):1335–55.

20. Markt A, Björkstén B, Granström M. Immunoglobulin E responses to diphtheria and tetanus toxoids after booster with aluminium-adsorbed and fluid DT-vaccines. Vaccine. 1995;13(7):669–73.

21. Terhune TD, Deth RC. How aluminum adjuvants could promote and enhance non-target IgE synthesis in a genetically-vulnerable sub-population. J Immunotoxicol. England; 2013;10(2):210–22.

22. Terhune TD, Deth RC. A role for impaired regulatory T cell function in adverse responses to aluminum adjuvant-containing vaccines in genetically susceptible individuals. Vaccine. Netherlands; 2014 Sep;32(40):5149–55.

23. Shoenfeld Y, Agmon-Levin N. “ASIA” – autoimmune/inflammatory syndrome induced by adjuvants. J Autoimmun. England; 2011 Feb;36(1):4–8.

 24. Kattan JD, Cox AL, Nowak-Wegrzyn A, Gimenez G, Bardina L, Sampson HA, et al. Allergic reactions to diphtheria, tetanus, and acellular pertussis vaccines among children with milk allergy. J Allergy Clin Immunol. 2011;Conference(var.pagings):AB238.

25. Nygren-Babol L, Sternesjö , Björck L. Factors influencing levels of folate-binding protein in bovine Å milk. Int Dairy J. 2004;14(9):761–5.

26. USDA Food Composition Databases [Internet]. Available from: https://ndb.nal.usda.gov/ndb/

27. Ramaekers VT, Sequeira JM, Blau N, Quadros E V. A milk-free diet downregulates folate receptor autoimmunity in cerebral folate deficiency syndrome. Dev Med Child Neurol. 2008;50(5):346–52.

28. Arumugham V. Epidemiological studies that ignore mechanism of disease causation are flawed and mechanistic evidence demonstrates that vaccines cause autism [Internet]. 2017. Available from: https://doi.org/10.5281/zenodo.1041905

29. Baydar T, Nagymajtenyi L, Isimer A, Sahin G. Effect of folic acid supplementation on aluminum accumulation in rats. Nutrition. United States; 2005 Mar;21(3):406–10.

30. Yassa HA, George SM, Mohamed HK. Folic acid improve developmental toxicity induced by aluminum sulphates. Environ Toxicol Pharmacol. 2017;50(Supplement C):32–6.

31. Zhu M, Li B, Ma X, Huang C, Wu R, Zhu W, et al. Folic Acid Protected Neural Cells Against Aluminum- Maltolate-Induced Apoptosis by Preventing miR-19 Downregulation. Neurochem Res. 2016;41(8):2110–8.

32. Mold M, Umar D, King A, Exley C. Aluminium in brain tissue in autism. J Trace Elem Med Biol. 2018 Mar;46:76–82.

33. FDA. Study Reports Aluminum in Vaccines Poses Extremely Low Risk to Infants [Internet]. Available from: https://www.fda.gov/biologicsbloodvaccines/scienceresearch/ucm284520.htm

34. Pulendran B, Ahmed R. Immunological mechanisms of vaccination. Nat Immunol. United States; 2011 Jun;12(6):509–17.

35. Arumugham V. SHINGRIX vaccine is unsafe and its approval must be revoked [Internet]. 2017. Available from: https://www.zenodo.org/record/1038302

36. FDA. SHINGRIX vaccine package insert [Internet]. 2017. Available from:



An Epiphanic Epitaph for the Coming New Reality of Science


Science sits on a threshold of a new reality, and while not begging special knowledge, the majority of scientists have seen it coming but only now are able to allow themselves to consider it.

Science is embarking on this new reality, as occurs in so many revolutions, by casting off the illusion of its masters. Perceptions of control warp the mind, and struggles for reconciliation, and pleas for acceptance are neither harmless to knowledge, nor our ability to perceive it. There is an alpha in the process of science, which begins with admission of ignorance, polluted by specks of presumed knowledge, sometimes tainted with hubris. And the structure of Logos then proceeds, like a broken algorithm, in fits and starts, toward an approximation of a process we amusingly in retrospect call discovery. The Dominants in science seek validation, through quantitative measures of their own success, of their own primacy. Both the measures and their social primacy eventually show themselves, to be both temporary and false. The Betas seek to find, in this hot mess of Science, some validation of understanding, which has a longer run, but which is also eventually replaced, sometimes for the better, sometimes for the worse. Many feel their way through science, which is incorrect, for rational discourse demands logic; however, it is also a myth that feelings have no place in science. The scientist in control of their faculties use reason to decide what things to have feelings about, but not necessarily how to feel about those things.  The scientist who gives that control to others has sold the tools they need to thrive, like a painter selling their brushes, or a sculptor selling their tools.

There is only but one nemesis of knowledge and that is ignorance, which itself is not always innocent; at time it is foisted upon the public when the processes of science pose perceived threats to a paltry coherence that holds some in power, which itself is also a placeholder in the longer time frame of history. An ethos for The New Science is to not seek the lost civilization, nor the forgotten knowledge in eons long past, except as a child pondering an amusement park. Seek instead what we are losing each day in the exponential orgasm of information production without reflection; seek what is lost by ignoring the moments between; seek to know what others know and credit them profusely for the grains of truth they stumble upon. Seek to hold on to what will be forgotten and lost to time if we fail to recognize it. Use the most robust tools, the most powerful designs and tests for deducing from without, not inducing from within, the next slippery sliver of something that might be knowledge. And when all else fails, do not settle for merely adding or pruning leaves from the Tree of Knowledge.  Instead, shake it at the base, question its assumptions without hesitation or apology, explore the what-if possibilities of alternative growth patterns and run the simulations in your mind on possibilities if past false assumptions and conclusion deep in the heart of the wood had been, at THAT time, recognized to be incorrect, or incomplete.  Because rest assured that many, if not most, will be discovered to be wanting, perhaps in our equally conceited now, or in some distant objective, reflective, demure and retiring future foolishly satisfied with its own imperceptible foibles.  When rot sets in, it is necessary, and the duty of every scientist, to dig the tree of knowledge up, to examine its roots for the healthiest parts, and then to plant and nurture those for a new beginning, which begins at the start of the story, not only at the end.  And most of all – now this is important – become and remain an activist for objectivity, reason, deduction, and passionate impartiality. That in and of itself is a goal, not a prescription.

If, in all of this endeavor, you manage to make some money while generating knowledge, more power to you.  But remember two things:

(1) money should be side-effect of a robust science, and, if you are “successful”

(2) use all three (money, knowledge, and power) wisely.

-James Lyons-Weiler, PhD

Allison Park, PA

May 2, 2017

The Slaughtering of our Constitutional Rights

JOHN STUART MILL is sometimes attributed with the quote “Your right to swing your fist ends where my nose begins”.  In reality, the quote seems to have arisen during prohibition protests.

Everyone understands that there are times when individuals must be called upon to secure our liberties and rights as a nation, at the risk of cost to individuals. The military draft, for example, is seen by many as a necessary evil from time to time, but even the de facto suspension of individual liberties during the draft is seen as extraordinary – no draft would be acceptable during a non-emergency period. The draft, for example, would never have been acceptable during Bush’s elective war in Iraq.

Lately there have been moves on the part of governments and other organizations to reduce, limit, or remove individual liberties and rights, and a full accounting of which rights are impinged in the name of saving humanity from infectious diseases seems worth considering.

1st Amendment Right to Free Speech

I was stunned to read a legal “scholars”‘s treatment of the question of whether we should tolerate free and open discussion of questions of vaccine safety. Claiming that discussing vaccine safety was akin to “shouting gunfire in a crowded theater”, the authors of the article in the Jurist concluded that perhaps American citizens’ rights to discuss their knowledge of the risks of vaccination should be rescinded.

Luckily, the issue was aptly taken up by Mary Holland, a legal scholar at New York University, who wisely stated (in brief) that the right to yell “gunfire” becomes a moral imperative when gunfire has, indeed, erupted in a theater.

Rights to Informed Consent

Vaccine defenders trample all over individuals’ rights to informed consent for medical procedures, both inside and outside the doctor’s office. Inside the office, they routinely deny informed consent by minimizing what is known about risks of vaccine injury, both in terms of the diversity of injuries that may occur, and their frequency. Patients who ask too many questions about vaccine injury are seen as problematic, rather than being seen as exercising their right (in all states) to know specific risks.  Information on the known HPV vaccine adverse events provided by your doctor are incomplete, and if you ask for the vaccine insert, you will find that it, too states that it is incomplete in its listing of the known adverse events, and it refers you back to your doctor for a full list!

If patients or parents decide to exercise their legally guaranteed right (in 47/50 states) to refuse vaccination, or to modify the schedule, or to skip or delay any specific vaccination due to their individual concern over risk, they are treated as problematic by healthcare workers, including medical doctors and office staff. The disdain and disregard for the law in such a setting by medical professionals is obvious.

California bill SB277 is a highly contested example of a state overreaching the authority intended by previous cases. It specifically strips Californians of the right to non-medical exemptions, and those who persist in exercising their Federal rights to refuse medical treatment once fully informed of the risks are stripped of their rights to access a public education, a right specifically provided by the California state constitution.

AAP Codifies Patient Harassment and Abrogation of the Hippocratic Oath

Doctors and healthcare workers around the country have been reported to use coercion, shame, and threats to deny patients access to medical care if they are vaccine-risk aware, and choose any of the legally provided options other than the CDC schedule. Last week, the AAP codified this disregard for the law by approving pediatricians’ practice of refusing to provide medical treatment to citizens who exercise their legal rights to non-medical exemptions. Citizens in nearly every states with mandatory vaccination for school attendance have the right to exercise religious, philosophical, moral and personal belief exemptions, whether pediatricians like it or not.


Sept 2016: Forty-seven states honor individual and parental rights to refuse vaccination – without their doctor’s permission to do so. AAP, CDC, and Pharma want that number to be ZERO.

In some states, the medical community has tried claim that doctors should ascertain for the state whether a person’s request for a religious exemption is genuine. Such laws and practices  are clearly a violation of the freedom of religion, which is a constitutionally protected right provided in the religion clauses of the First Amendment.  A moment’s review of the contents of some vaccines (aborted fetal cells, pig products) will reveal that recipients who are forced to receive those contents into their bodies are also being forced to deny central tenets of their faith.

Across the US, patients are denied informed consent in myriad other ways as well.  The fact that pharmaceutical companies are exempt from liability prevents news stories of companies held accountable for harm – and also prevents motivating companies from making vaccines safer.  Instead, consumers pay a tax on every vaccine to pay damages via the National Vaccine Injury Compensation Program – which sounds good, until one realizes how extremely tortured the logic has been to make vaccine-induced encephalopathy a replacement vaccine injury for autism so the program does not have to pay for vaccine-induced encephalopathy-mediated autism.

Right to Refuse Medical Experimentation

After the Nuremberg trial, it became both common international and national law in the US that no citizen shall be subject to medical experimentation without their express, fully informed consent. The law that protects American citizens’ right fall under the FDA’s domain, which requires that all medical researchers conducting human subjects research acquire specific consent after reviewing the full list of known and potential risks associated with experimental drugs and medical procedures.

Much of what the CDC calls vaccine safety research is conducted using post-market surveillance. US citizens are not informed that their reaction to a given vaccine may be used by the government or government-funded researchers to assess vaccine safety. By definition, then, we are all enrolled in an uncontrolled medical experiment without consent. We are never given the opportunity to refuse to be enrolled in this massive medical experiment. Not that it matters much for the sake of the science; the studies conducted using data from the passive Vaccine Adverse Events Reporting System (VAERS) and the Vaccine Safety Datalink (VSD) are nearly universally retrospective descriptive correlational studies, and thus any suggestion or hint of increased rates of serious adverse events can easily either be cooked away by repeated rounds of data analysis (analysis-to-result), as has been the practice at the CDC for studies on the question of vaccine-induced encephalopathy-mediated autism, or the results can be dismissed as merely ‘correlational’.

When a new vaccine is being added to the CDC pediatric schedule, the prospective studies that are conducted do not test the cumulative effect of the vaccine schedule against unvaccinated individuals, but rather existing schedule vs. modified. Those that do use ‘placebo’ tend to use the adjuvant (additive designed to enrage the immune system) vs the vaccine, and thus the rates of mild, moderate and serious adverse events for vaccines are unknown.

13th and 14th Amendment Rights: The only way so far to identify individuals – and families – who are at risk of vaccine injury is to vaccinate them, and thereby injure them. These subgroups of individuals are potentially identifiable – if only research priorities allowed us to focus on the development of biomarkers to predict who might be at risk of specific harm. In America, minority citizens have, under the 13th and 14th Amendments, the rights to equal protection. The first step to predicting who among us are at special risk is to admit that vaccines cause harm. In denying the link between vaccines and autism, not only are the rights to informed consent denied, and rights to compensation for harm being denied, but the right to protection by the state as a genetic minority are also denied because the science to identify specific biomarkers for specific serious adverse events for specific subgroups cannot be conducted when autism denialists write the rules.

CDC Proposes Their Totalitarian Rule

In a stunning move made under the guise of medical emergencies caused by emerging infectious diseases, CDC has proposed new rules for themselves to be able to apprehend and detain American citizens indefinitely, without access to legal counsel; to disallow citizens’ rights to cease communicating with the CDC (First Amendment; Fifth Amendment); to access (without consent) our electronic communications (Fourth Amendment); to forcibly vaccinate American citizens against their will (Rights to Informed Consent); and to deny them any compensation whatsoever for any harm done to them physically  or to their attempts to enjoy their rights to life, liberty and the pursuit of happiness.  Defenders will say that this is only for instances in which an emergency has been declared, and they list specific diseases for which they imagine they may have to impose totalitarian rule (Ebola, Marburg, and others (see a full accounting by James Grundvig here). They also, of course, give themselves the right to add more diseases, and thus vaccines, to this list. CDC wish to grant itself open-ended police powers in a manner that is not only not consistent with the Constitution: their power grab is not consistent with America.

I am sure that I have not fully counted the number of rights seized by the CDC Totalitarian Rule, but they must be stopped. They should not be granted powers to suspend most of the Constitution.

CDC employees have an odd, paramilitary culture that is not necessary in a free and open society.  Perhaps they are nervous and this bluster is a threat. Perhaps they will apprehend people who write blog articles. Perhaps they will apprehend people who make movies. Perhaps you will be arrested by a Rear Admiral and force-vaccinated against all of these diseases because you told your sister about “The Environmental and Genetic Causes of Autism“.

We must immediately, forcefully and collectively assert and affirm our rights to:

  • Rights to Free Speech
  • Religious Rights
  • Rights to Refuse Medical Treatment
  • Right to Refuse to Participate in Medical Experiments
  • Rights to Equal Protection
  • Life, Liberty and the Pursuit of Happiness.


The reality is that open-end legislation at Federal, State, and County levels on vaccine mandates are dangerous, because no science is done to tell us about the risks of adding an ever-increasing number of vaccines, and this newly proposed ’emergency’ authority to force vaccination upon American citizens a list of vaccines to which CDC can add at their whim cut deep across the grain of American sensibility and our traditional respect for the rights of individuals.

The attack on Constitutionally guaranteed and protected rights being visited upon the American public is sometimes described using the word “impingement”.  The aggregate effects of these moves is not an impingement – it is a dismantling of our safeguards against a totalitarian state. It’s a wholescale slaughter of the Constitution.

What are your thoughts? What other rights are being threatened by vaccine risk denialists?  Let’s have #thediscussion – while we still can.


The Constitution of the United States of America

Holland, MS. 2011. Legally Censoring Speech on Vaccines and Autism: A Response. The Jurist http://www.jurist.org/forum/2015/12/mary-holland-vaccines-autism.php

Vaccine Safety Datalink

About the Author:

Dr. Lyons-Weiler is the CEO of The Institute for Pure and Applied Knowledge, former Senior Research Scientist and Scientific Director of the Bioinformatics Analysis Core at the University of Pittsburgh, and former faculty member in the Department of Pathology and Department of Biomedical Informatics (University of Pittsburgh), and former full faculty member in The University of Pittsburgh Cancer Institute. He is the author of three books (Ebola: An Evolving Story; Cures vs. Profits: Successes in Translational Research and The Environmental and Genetic Causes of Autism). To book Dr. Lyons-Weiler for speaking engagements, email ebolapromo@gmail.com

Visit Dr. Lyons-Weiler’s Facebook author page.

Protect Baby’s Brain from Aluminum Neurotoxicity – It’s Not Just the Vaccines

Anyone who reads my writings will know that I tend to not hold back in the “should” department – because ethics and morals in society depends not only in the proper conduct of science, but also in the proper translation into general knowledge and public health policy.  Those with their hands on the reins of public health policy appear to be more interested in defending flawed policies, and those of us who have come to learn of flaws in the science used to bolster those policies are bound by moral contract with a duty to warn our fellow human beings.

Well, at least some of feel that way.

I would be worthy of being labeled hypocritical, therefore, if I did not shout from my blog the news that there are other sources of aluminum that pregnant and nursing moms may well expose their developing babies to – one that is so commonly available, and the dose of aluminum so high that I shudder to think of any pregnant woman or nursing mom (or individual who likes their brain) taking a single dose.

That product is antacids.

In a chapter reviewing aluminum neurotoxicity (yes, Dr. Offit, aluminum is a long-known neurotoxin), Dr. Robert Yokel in 2012 reviewed estimates of the amount of aluminum absorbed from exposure from various sources, and the results certainly do not bode well for vaccines.  Here is a screen shot of the chapter:


And here is a screenshot of his Table 1, with aluminum from vaccines at 0.07ug daily exposure and aluminum from antacids at 80ug per day:


The low amount calculated “per day”from vaccines, however, is misleading: the dose from a vaccine is given in a single day – and the body has to deal with 100% absorption in real time.  So the numbers to compare are 12-300µg/dose in a day to 80µg/day.  Se the “up to 5,000,000 µg” ingested?  The fact that only 80µg are absorbed per day shows you how little aluminum a normal-functioning GI tract actually absorbs. But that’s a lot for a mom to have in her body while she’s pregnant.  So much for the dismissive position that babies get more aluminum from baby formula. Mothers should breastfeed anyway – unbelievable, CDC recently said moms should not breastfeed to give the vaccines a chance to be more effective.

Add to the 80 from antacids and aluminum in the vaccines offered during pregnancy (bad idea in the first place), and add later aluminum to the baby after via vaccines after birth, you can see we may successively and repeatedly dose our youngest with a neurotoxicant. Aluminum (in a wide variety of forms) causes chronic microglial activation, which occurs when certain cells (microglia) in our brains get stuck in the “destroy” mode and take out dendrites trying to make connections and baby nerve cells (neural precursor cells).

Expectant moms, lactacting moms, throw your antacids away and look at your aluminum intake.  Other foods potentially high in aluminum include pre-prepared pancake mixes and other foods that are kept powdery and dry.  Look at the ingredients and save your baby’s brain from chronic and prolonged exposure.   Get an air filter and filter out the dust that can introduce aluminum into your baby’s body via the lungs or GI tract.

Aluminum is certainly not the only toxin that can induce microglial activation. But 10% of the aluminum absorbed stays in the brain for decades.  Moms and dads, look at the table an find ways to reduce aluminum exposure, and we might just be able to reduce the rates of autism/ASD worldwide.

The full chapter is available from the University of Kentucky website.


baby brain


Dr. Lyons-Weiler is the author of three book, the latest of which is “Environmental and Genetic Causes of Autism”, which can be ordered online or from your local independent bookseller. A companion website to the book includes over 1,000 references to studies on autism.


My Journey from Ignorance

WHILE RETURNING from the United Nations building where I heard NYU Professor Mary Holland (School of Law) nail the issues of constitutional and international law on the right to informed consent to the floor, to a standing ovation, I received an email from Mary ( To my delight). I read, in part:

“I  started reading your Ebola book last night.  Wow, you have evolved a lot in your thinking on vaccines in a VERY short period, based on your definition of ‘antivaxxers’ at bottom of 206, top of 207.  Have you written up how your views evolved so quickly?  It might be a helpful roadmap towards turning others around.  Was this all in connection with the autism book, or did your views changing precede that book?”

Looking at my book this morning, I turned to page 206, with trepidation, to find the younger, knowing me, trying to save the world by chiding and deriding people whom I have come to learn much more about in the past two years:

“Again and again with Ebola we see, from Guinea to the US, societies struggling with the ethical problem of the needs (and wants) of a few vs. the safety (and lives) on the many”.

Ok, that’s not too bad.  A bit uppity, but I cannot disagree. But it gets worse.

“With over 100 cases confirmed, the US is, at the time of this writing, at high risk of an epidemic of measles because the herd immunity is lacking due to a dogmatic antivaccination movement”.

I warned you.

Deplorably, I continue:

“The efficacy of the measles vaccine in protecting children against terrible diseases should be reason enough for parents to insist on vaccinating their children, but the so-called ‘anti-vaxxers’ (people who believe vaccines place their children at risk of developing autism) fail to consider the greater good: They put others at risk by not participating in national programs for the greater good.”

I really do not like my former self. Naturally, I continue, because I knew SO much before I actually looked into the studies and the data:

“This perspective is more than mere 20:20 hindsight; such occurrences of cultural and institutional amnesia are certain to recur as our society becomes more reliant and trusting in technology, and we forget to respect the awesome power of biology and Nature”.

I really don’t know this guy, I swear.

Mary Holland will certainly be remembered as one of the most staunch defenders of human rights, well, in the history of abuses in medicine. So back to Mary’s question:

“Have you written up how your views evolved so quickly?  It might be a helpful roadmap towards turning others around.  Was this all in connection with the autism book, or did your views changing precede that book?”

Here’s how and why my views have changed. First, I was really rather upset about the fact that CDC Director Thomas Freiden stated in his testimony to Congress that there were no mutations in the Ebolavirus that was driving the epidemic.  I was upset because I had the 396 mutations on my laptop at the very moment he testified to Congress.  I capture that moment in “Ebola“. My anger at the CDC increased when I attended a secret White House conference call, held by the Ebola Czar, in which I asked about the 396 mutations – whether they influenced the ability of tests to detect Ebola, or altered its virulence or transmissibility. In that call, the entire scientific community was lied to again by a CDC Scientist who claimed that the virus was “99.9999% identical to the strain from Zaire in 1995”, which was not true at all.  I capture both of those events in “Ebola”, as well as how the White House then asked the Associated Press to stop covering potential cases of Ebola in the US.  I even ask in that book whether that was “fascism”.

Fast forward a couple of months to where I had decided to write “Cures vs. Profits“. I felt that we had bungled our response to Ebola so badly that I wanted to cheer myself up and write a book on the successes in biomedical research.  Having participated in so many studies over the past two decades, I knew of many reasons that the public should continue to support biomedical research, and I was going to share all that I knew, and discover more. The first two chapters deal with “the bad stuff” – the doctors who cheat at medicare fraud, which robs other patients of needed funds for real medicine – and the biomedical researchers who cheat at their research studies.

I wrote my chapters out on grapefruit, on cancer vaccines, on prostate cancer robotic surgery, and then something happened: I wrote a chapter on ADHD overdiagnosis. I tell the story of the destruction of a promising career of Dr. Gretchen Watson.  Pharma sent a “Key Opinion Leader” to EVMS to debate her over her study, and the next day she was told her case load was canceled, that her colleagues were told that she no longer worked at EVMS, and that she was to expected to resign.  She refused, and won an appeal to HR.  But then someone floated a rumor that she manipulated her data in the 1996 study showing overdiagnosis.

The investigation revealed no flaw – well, a typo in an appendix – but the damage to her career was done. The good news is that Dr. Watson has decided to write of book of her own after reading my chapter on ADHD.  She now also serves on the Board at IPAK.

When I finished writing the rest of “Cures“, including chapters on the history of hormone receptor status in breast cancer, chemosensitivity assays, characteristics of good research scientists, and cancer vaccines, I found the book missing something.

So I decided to write a chapter on Vaccines.

I’ll let the chapter on vaccines speak for itself- it begins with tales of how wonderful vaccines are, how they save lives.  I went back to review the autism/vaccine link, fully expecting to review the Andrew Wakefield issue briefly, how his claims that MMR were linked to vaccines. I read the retracted study.

I found that Andrew Wakefield never claimed that the MMR might cause autism.  Instead, I found the study to suggest that it was a question worth looking into.

My digging around then led to my discovery of reports that someone at CDC had revealed that CDC had manipulated data on the studies designed to disprove Wakefield by omitting results with a positive association.

The more I dug into the issue, and then into the literature, the more I found the science of vaccines falling far short of the science needed to insure public health via any medical procedure given to millions. And this is where I leave the issue in “Cures“. I added an addendum that reviews four open controversies in vaccines that cause me to question whether vaccines can be called an unmitigated success in translational research.

In retrospect, I see that position as something of an understatement.

My understanding of vaccines was (obviously) limited, and I needed to grasp the risks involved. I needed resolution. So after I completed “Cures“, I began writing about what I had learned. I spoke with people with an open mind. I started to listen not only to what these evil, selfish “anti-vaxxers” had to say, I started to really think about the consequences of the additives. I began to question the over-arching claims of safety.

And via some new contacts, I made connection with Tony Lyons of Skyhorse Publishing. After a few chats, he, Louis Conte and I agreed that I should write a book on the Genetics of Autism. (I love Louis – and knowing what I know of him now, my bet is that he thought I was a good prospect – but somehow I can hear him telling Tony that Jack has ‘a way to go, but I think he’ll get there’. Thank you Louis for the confidence.

So in I dove, into 3,000 research articles on autism.  Not on vaccines – on autism.  I wanted to know if the basic science could in any way reasonably support a hypothesis that vaccines or their additives cause autism. The answer is a resounding “Yes, yes, and yes”. Other articles in this blog will give you an idea of some of the evidence that exists on the role of chronic microglial activation and autism, for example.

To the readers of “Ebola” who feel confused or hurt by my, and others’ ignorance, please remember that there is a Great Unknowing, even among professionals.  Think about it – all “Anti-vaxxers” with vaccine-injured children were once pro-vaccine. As I advised some 500 participants at the VIALs Health Summit in Atlanta, GA, do not argue with them – educate them. Your anger and frustration is warranted, but help them move from ignorance to awareness and understanding.

I took it upon myself to consider 3,000 articles on autism for “Causes” (available at Amazon.com and in your local Barnes and Noble or indie bookstore).  (I skimmed 3,000, read >2,000, and cite >1,000). Look at what knowledge can do to a scientist who themselves feel cheated and lied to, someone who entrusted the CDC to perform objective science (See “The Tyranny of Pseudoscience“):


The author at a CDC Rally, April 22nd, 2016.



Educating the public and calling for Congress to Subpoena Dr. William Thompson at the CDC on the true nature of so-called “Science” conducted at the CDC on the link between vaccines and autism.

To My Fellow Scientists and Medical Health Care Professionals

I wrote “Ebola” in good faith, assuming that the position of the CDC on vaccines was based on sound science. It was unfathomable to me that

-Upon finding positive associations, CDC would routinely over-analyze data from studies until they could make associations go away, and when they could not succeed in doing that, they would simply omit the results;

-CDC would suspend an employee who drew these practices to the attention of then CDC Director Dr. Julie Gerberding (who subsequently took a position in charge of vaccine development at Merck);

-After CDC published these studies they called for an end to research on vaccine safety with regard to potential links to autism;

-CDC would ignore nearly all of the basic science that shows mechanisms of how neurotoxins in vaccines (not just MMR) could reasonably be expected to cause autism in some people;

-CDC’s position is based on ecological association studies, not randomized prospective clinical studies with proper controls.

-Our knowledge of vaccine safety is based on post-market surveillance;

-CDC would ignore all of the post-market surveillance on vaccine safety, claiming that the passively collected data in VAERS did not provide causal evidence;

-CDC would lie repeatedly under oath to Congress about the State of Science on the link between vaccines and autism;

-No one has ever conducted a vaccinated vs. unvaccinated study for association with negative health outcomes, including autism.

-CDC would communicate to the public that “Vaccines Do Not Cause Autism” on their website knowing full well that 6/12 vaccines on the schedule before the age of 7 have 0 studies one way, or the other, on whether they indeed may (or may not) contribute to the risk of autism.

I, like the rest of the world, relied on the CDC to be a reliable source of information on vaccine safety.  Yes, I vaccinated my children. I will not allow them to get the HPV vaccine. Here is why.

To the Parents of Vaccine-Injured Children who Regressed Into Autism

Your observations are the basis of a new era in vaccine science.  All science begins with observations. Help and relief is on the way. And there is nothing that can stop it.

Dr. Lyons-Weiler (right) meets Marcella Piper-Terry (left) at the 2016 CDC Rally.
Fellow Vaccine Risk Aware Protestors Calling for Congress to Subpoena Dr. Thomspson
Dr. Lyons-Weiler meets the future Director of the CDC.

After the Rally, we enjoyed a summit at Life University hosted by VIALS. Here was our audience:


Here I presented the CDC Schedule as backed by “Magic”, because no science exists on any link between 6 vaccines and autism, whereas some vaccines do, in fact have some studies that support association:

no science 2no science

That was a good day in Atlanta, GA. Here are the slides to share with your pediatrician:

VIALs health summit slides James LyonsWeiler MAGIC




Next stop, the United Nations:




Dr. Lyons-Weiler attends a UN Session on Toxins in Our Children, April 26th, where Dr. Thompson’s revelations were shared with the world.


Mary Holland standing up for your rights to refuse medical procedures as a basic human right. To watch the unprecedented UN Session on Toxic Contamination of Children (4/26/2016), follow this link.

Mary Holland’s question to me was an important one:like many, if not most other professionals, I had argued my position on the vaccine/autism question from a position of ignorance.  They simply have not done their homework, and many have bought the CDC’s lies hook, line and sinker. They count on CDC to be honest and forthright. This include the AAP, the AMA, and, very likely, your pediatrician.

Most of them probably have not read a single study. They likely have never read the following words that Dr. William Thompson said to Dr. Hooker:

Thompson: “They don’t really want people to know that this data exists.”

Thompson: “…among the blacks, the ones that were getting vaccinated earlier, were more likely to have autism.”

Thompson: “It appears in the final publication is that race in general is downplayed. Of course it is.”

Thompson: “I actually think the most interesting results are the isolated, ones that don’t have their co morbid conditions. The effect is where you would think it would happen.”

Thompson: “I was just looking at—I was like, oh my God, I cannot believe we did what we did. But we did.”

Thompson: “The higher ups wanted to do certain things and I went along with it. In terms of chain of command, I was number four out of five. “

Thompson: “…Literally, everyone else got rid of all their documents, and so the only documents that exist right now from that study are mine.”

Thompson: “There are things that I haven’t even shared with you because I can’t prove it, and that’s what I struggle with. I don’t want to share things with you that I can’t prove, that there aren’t hard records. I am worried that the other four people will collude and say no, that’s not true.”

Thompson: “That’s what I keep seeing again, and again, and again where these senior people just do completely unethical, vile things and no one holds them accountable. “

Thompson: “The reason you don’t see anything else circulating on the study, it was five of us behind closed doors for two years.”

Thompson: “It’s the lowest point in my career that I went along with that paper.”

Dr. William W. Thompson

My book “Cures vs. Profits” tells more of the story of Dr. Thompson and Hooker. At this point, I am willing to go on the record and say that I have zero – ZERO confidence in any science coming out of the CDC Immunization Safety division. And no one else should trust their research, either.

In fact, nothing they publish can be trusted. Not merely because of what Thompson said.

I’ve read their studies.

They are atrociously unsafe ventures in data cooking, model overfit, sad excuses for “control variables”, use of multicollinear variables, the product of repeated data analysis to a desired result (no association). They are a mess.

The individual people in question include

RADM Anne Schuchat, Principal Deputy Director of CDC

Dr. Frank DeStefano, Director of the Immunization Safety Office

Dr. Coleen Boyle Director, National Center on Birth Defects and Developmental Disabilities (NCBDDD)

Dr. Poul Thorsen (co-author on suspect CDC studies, wanted by HHS for embezzling over $1Million in funds that were to be used for autism research, living openly in Denmark).

and others.

In my research, I strive to remain objective. However, since 2004, when the research fraud at the CDC occurred, there have been over 1,000,000 cases of autism that potentially could have been prevented simply by splitting up the MMR into three vaccines, spacing the vaccines out, giving non-adjuvanted vaccines with 1 adjuvanted, screening for safe epitopes, removal of mercury from all vaccines, giving medical exemptions to parents who already have one autistic child (to avoid the genetic x environment interaction), dropping HepB until adulthood… so many simple things that could have been done to reduce early exposures to toxins. Where is the science for biomarkers to indicate which children might be most at risk of ASD due to vaccines?  Not done.  CDC called for no more science.

We Want Evidence-Based Public Health Policies, not Policies Based on Subjective Belief (aka “Magic”)

Right now, the so-called “Anti-vaxxers” I so woefully admonished in “Ebola” are not all “Anti-Vaxxers”. They do consist partly of some people who believe no safe vaccine could ever exist. I respectfully remind them that until the science is done to show that non-adjuvanted vaccines without mercury, aluminum, formaldehyde, etc are tested, their knowledge claim is an untested generalization about all vaccines. Out of well-deserved distrust, they call for no more science on vaccine safety – because they know that some will be injured by that very research.

But the Vaccine Risk Aware movement also includes people who are 100% Pro-Vaccine Safety. They suspect that safe and effective antigen presentation systems can be designed, that use exposure at the skin (microdermal abrasion), with epitopes that do not induce autoimmunity. They believe that taking the toxins out will likely make vaccines safer. But they do not make such claims.  They call for more science, not less, but on newer options for inducing immunity.

To watch my presentation at the VIALS Health Summit State of Science on Vaccine Safety: Autism, in which I explain how the CDC’s claims that vaccines do not cause autism must be based on magic, follow these links: (Part 1, Part 2, Part 3).

Calls for Retraction of CDC “Studies”

Because CDC committed scientific fraud, the studies they performed should be retracted. IPAK has informed the journals of this, and we have sent them copies of “Vaccine Whistleblower, by Kevin Barry, Esq.

I urge all of my colleagues to view the movie #Vaxxed.  Call your local theater and ask them to screen the movie. If you consider yourself an objective scientist, read “Whistleblower“, and RFK jr.’s book, “Thimerosal: Let the Science Speak“.  Order “Master Manipulator” by James Grundvig, which tells the story of Poul Thorsen, a CDC collaborator wanted for absconding with autism research cash (given what CDC would have done with the money, Thorsen may be a hero, for all we know).  For a deeper timeline view on how long corporate corruption has eroded science in our most esteemed institutions like the CDC, read “Science for Sale” by David Lewis.

I ask my professional colleagues from all walks of science and medicine then to join us in our calls for retraction of the CDC’s false studies: DeStefano et al., Madsen et al., and Verstraeten et al.  I will not stop educating professionals about the fraud because we need evidence-based medicine, not medicine based on guesses, or hopes, or magic.  Babies are dying in the womb due to mercury in flu vaccine reserved for pregnant women; babies are born autistic due to immunoneuroexcitotoxicity; they are born with seizure disorders; toddlers regress into autism after learning language. And yes, it may be due to cumulative and interactive effects of toxic chemicals from agriculture, industry, our home, etc.  But we can reduce the toxins we expose our children to.  Right now, autism risk is 1 in 68, up from 1 in 3000 in the 1970’s.  Let’s have #theconversation.



Acknowledgements. I have literally thousands of people to thank for helping move from ignorance to awareness.  You know who you are. Thank you.

Please support VIALs with a generous donation.  Tell them Jack sent you!
To support Dr. Lyons-Weiler and his research associates at IPAK, visit ipaknowledge.org

VIALs health summit slides James LyonsWeiler MAGIC


“You Know Nothing About Autism, John Snow”

IN THE TELEVISION PRE-HISTORY FICTIONAL MINISERIES ‘GAME OF THRONES’, a female character named Ygritte is fond of telling her lover, a Night Watchman, who lives caught between two warring cultures, the expression “You know nothing, Jon Snow”.  She tells him this to remind him that he has no idea why the Wildings, a tribe of undead people, are attacking their peoples, and, as hint to the fact that in spite of their different origins as people, she loves him.s


There is another Snow of merit who lived between cultures – a culture of science and a culture of stoic and unforgiving ignorance. This John Snow has an important lesson for our time.

In 1854’s, London Physician John Snow was confronted with a severe outbreak of cholera.  The prevailing view of the cause of the cholera at the time was the ‘miasma’ theory, in which ‘bad air’, or something called ‘vibrones’ which the medical community postulated caused the spread of the illness.

London’s Soho District at the time was typical of London neighborhoods in the 1850’s.  Most homes had cess pits under their homes for human waste, and if the waste production exceeded the soil’s capacity, it would he hauled away, for a fee, and dumped into the river Thames.

The good Dr. Snow, pictured to the right, was not satisfied by the miasma theory. As the cholera outbreak worsened, he began mapping cases and eventually recognized that most John_Snowcases were clustered near a water pump on Broad Street. His careful observations led him to conclude that whatever ‘cholera poison’, as he referred to it, was behind the outbreak, it was somehow connected to the water pump. This was before germ theory was established and pathogens such as bacteria and viruses were unknown to medicine.

A religious colleague, The Reverend Henry Whitehead, from St. Luke’s Church, was a believer of the miasma theory. As any good man of the church would so, he attempted to disprove theories, and when he turned his attention to Dr. Snow’s theory of that cholera was a water-born illness, somehow connected to human waste, he was turned away from the nondescript miasma theory by the evidence accumulated by Snow in his maps. He even accompanied Dr. Snow on a hunt for the connection between human waste and the water pump, and together they discovered a home that had a cess pit that drained to a old cess pit only a few feet away from the well at the Broad Street Pump. The homeowners routinely dumped diapers (nappies) into the cess pit under their home.

Together, Snow and Whitehead convinced the town’s government to break the handle off the pump. Thereafter, the cholera epidemic ceased; however, the government (The London Board of Health) refused to acknowledge the links between human waste, water and cholera, instead sticking by the ill-defined miasma theory. (Beer drinkers, rejoice – the villagers turned to beer for their liquid intake – which of course was free from cholera due to the fermentation process).

CDC’s Miasma Theory of Autism

John Snow’s Original Map Showing Clusters of Cholera Around the Broad Street Pump, 1854


In their fervor to convince the public that no link exists between vaccines and autism, the CDC has neglected to propound (offer) any viable theory for the increase in autism. Others have tried to blame changes in diagnosis, or genetics for the rise in autism, but neither of these two factors can explain the incredibly rapid rise from 1 in 3000 in the 1970’s to 1 in 68. In fact, the CDC has shown a remarkable lack of curiosity about what DOES cause autism. The CDC’s amorphous theory of autism is, empirically, identical to the miasma theory for cholera – because neither vibrones, nor CDCs’ theory of autism exist.


Cherry Picking: CDC’s Woeful, Biased Representation of The Available Science

In all of their communications to the public on causes of autism, CDC fails to consider the bulk of the available science that not only shows association between autism and vaccines, but also points squarely to the role of aluminum and mercury as fundamental to the etiology of autism via chronic microglial activation. I know this because I’ve read the science the CDC has not read. Between November 2015 and February 2016, I read over 3,000 published and peer-reviewed studies on autism – not on vaccines intentionally – but rather on autism.  I took the position of  geneticist who wanted to know how traits as unique as autism – lack of or loss of language abilities, aberrant motor movements, differences in executive functions – might be explained considering both genetic and environmental factors.

What I found were studies that clearly showed that neurotoxins such as aluminum, (read this before you claim aluminum is not a neurotoxin), mercury, valproaic acid, thalidomide, and other toxins are picked up by macrophages, deposited in the brain, and interfere with astrocytic glutamate uptake. The excess glutamate prevents microglial cells from de-activating, once activated, and the microglia consume dendrites and neural precursor cells. The autistic brain becomes uni-polar, with many one:one axon:dendrite connections. The microglia in their activated form are not available to shepherd multiple axon:dendrite connections during reinforcement learning, and thus the structures for inhibition feedback are missing. The autistic brain allows perceptual signals to get into the brain too far, too fast, and this is why their are perception sensitivities to light, and sounds. There are also perceptual differences, more easily controlled by shutting down one eye, for example (the sideways glance forces the use of peripheral vision, which reduces the input level to tolerable, so autistic are actually try to look and focus and pay attention by such behavior, not ignoring you!). Further, the input signals can travel so far so fast throughout the brain that they can activate motor neurons, leading to repetitive and uncontrolled behaviors.

This is just a small part of what we know – the rest is in the book. There is much, much more that is known about autism than the CDC’s Miasma-like position would allow for. And all of this amassed knowledge, paid for by our tax dollars, conducted by researchers outside of the CDC, is ignored by the CDC and summarily dismissed as ‘unreliable’. Consider, for example, the interchange between Senator Elizabeth Warren and Rear Admiral Schuchat (excerpt from “The Environmental and Genetic Causes of Autism“:

“Massachusetts Senator Elizabeth Warren asked Dr. Schuchat a few questions and in each response, Schuchat reassured her that vaccines were highly safe and effective and that ‘dozens of studies’ had been conducted that showed no association between autism and vaccines.

Warren: Is there any scientific evidence that vaccines cause profound mental disorders?

Dr. Schuchat: No.


Near the end of her testimony, the following interchange occurred:

Warren: Parents should know that all of the credible scientific evidence suggests that modern vaccines are safe, modern vaccines are effective and modern vaccines are our best chance of protecting our children from diseases that can kill them, is that right?

Schuchat: That’s right.

The emphasis on “all of the credible scientific evidence” is mine, but the words are Warren’s, agreed to by Schuchat and they are critically important.

Schuchat dismissed most of the evidence cited in this book so far, which is a mountain of peer-reviewed, credible scientific studies. Since she agreed with Warren’s statement, Schuchat testified that all of the evidence that contradicted her own and the CDC’s conclusions was not credible.” – (James Lyons-Weiler, “The Environmental and Genetic Causes of Autism, (C) Skyhorse Publishing).

Here, Senator Warren, and the rest of the Senate, and by extension, the People of the United States of America are being lied to by the most senior ranking official in the CDC about not just a few paltry studies that might show links between vaccines and autism – but about ALL studies showing how, and why, vaccines can cause autism in some people.

That’s right. LIED TO.

The science that Schuchat is lying about is valid, and much of it is outlined in detail here, and in “Causes“.

Think about this misrepresentation the next time you hear someone say “the issue is settled” or “the science shows no link” or “all of the published studies show” no link between vaccines and autism.

Those statements are 100% incorrect. Here is the rest of the science.

Anti-Vax? Pro-Vax? How about a Third Option: SCIENCE.

The fact that the word is out that the CDC also omitted results from a key study, and over-cooked the data analysis as a matter of routine to make associations between vaccination and autism disappear – is scaring people. Like Schuchat. And Dr. Frank DeStefano. And Dr. Coleen Boyle. They have misled the public for over 15 years on autism. But more and more pediatricians are accepting that vaccines may cause autism, and therefore the CDC is fast becoming irrelevant. By fudging their results, they lied to their fellow scientists. They lied to the rest of the US Government. They lied to the People of the United States. They lied to Pharma. They lied to the FDA, the NIH, the NIAID, the AAP, the AMA.  They have lied to the Press. They have lied to the so-called internet ‘trolls’ who spend inordinate amounts of time insulting and demeaning the vaccine-risk aware population.

I have read the CDC’s so-called “science”, and I can see how they fudged their results. Remember, I’m an expert is multivariate and high-dimensional analysis. I know how to interpret a significant interaction term in a linear model – evidently the CDC apparently does not even know they exist.

The National Academy of Sciences and the Institute of Medicine rejected 17/22 studies put forward by the CDC as flawed. That leaves a scant 5 studies upon which our public health policy is based.


Given that they have tried so hard to warp our perception, I propose that we move on from the CDC – and start doing bona fide vaccine safety science. Every vaccine, all health outcomes. Let’s use Virus-Like Particles (VLPs), screened for epitopes that match important human proteins, and reduce autoimmune diseases. Let’s use VLPs with sufficient antigen loads so adjuvants are not required. Let’s make them sterile and free from preservatives.

Because vaccines are the water pump, and autism is our cholera.  Wakefield, Hooker, Schoenfeld, Shaw, Seneff, Gallager, Goodman, Delong, Sharpe, Tomljenovic, Geier and Geier, Young, Nataf, Yasuda, Tstusui,  Blaurock-Busch, Molina, Bradstreet, McDonald,
Singh, Holmes, Lee, Vargas, Poling, Mikovitz, Palmter, Mohamed,  and many others, especially Dr. Russell Blaylock and Dr. William Thompson of the CDC… these are today’s John Snows [1].

Today’s John Snows have been calling for us to clean up vaccines – not to break the handle off the pump – but to clean up vaccines, and to shut down the epidemic. They do not wish to ban vaccines.  Quite the opposite – their goals are to make them so safe that the myths of vaccine safety perpetuated by the CDC become true, and then everyone can enjoy the full benefits.  Their science – and it is valid science, regardless of what Rr. Adm. Shuchat tried – and failed – to get us to believe – has shined a bright light on what is wrong with the current formulation of most vaccines.

Here is the CSPAN video of the interview in which Rr. Adm. Shuchat dimisses with one word ALL of the available peer-review science the CDC has decided is unreliable (that is, any science the CDC has not done themselves.

You can help move vaccination science away from the everlasting debate by moving on from the CDC as well. (See IPAK). The CDC vaccine division and leadership have consistently proved themselves to be unreliable as a sources of information on the science of vaccines. We have many more qualified scientists outside of the CDC than inside of the CDC who are capable of performing vaccine safety research. Let us wrest it from the CDC and put it in the hands of the NIH, NIAID, or Department of Homeland Security, under the following model:

Every vaccine, studied for 4 years, each studied independently by 5 institutions (extramural), focused on efficacy, and safety, with proper research oversight – run the studies as randomized prospective clinical trials. Three (3) of the five institutions win contracts by lottery, and two by competitive peer review. This will break any chance of intrusion by monied interests. All should publish their studies independently. Each vaccine should be subject to approval by the FDA, with separate committees studying safety and efficacy.

Autism is a public health crisis – but then so is autoimmunity. We know that certain epitopes in vaccines induce autoimmunity. All epitopes in pathogens with clear functional mapping to autoimmunity (such as basic mylein protein) should be banned from use. And we should conduct genetic screening to see if we can predict which patients are most likely to suffer from adverse events from vaccines.

Let’s leave the handle on the pump, and clean up the water. Everyone will be happier, safer, and, most importantly, healthier. And the collective denial of autism/vaccines can end.

John Snow Memorial and Public House, Soho District, London.


Dr. John Snow’s report:

“On proceeding to the spot, I found that nearly all the deaths had taken place within a short distance of the [Broad Street] pump. There were only ten deaths in houses situated decidedly nearer to another street-pump. In five of these cases the families of the deceased persons informed me that they always sent to the pump in Broad Street, as they preferred the water to that of the pumps which were nearer. In three other cases, the deceased were children who went to school near the pump in Broad Street…

With regard to the deaths occurring in the locality belonging to the pump, there were 61 instances in which I was informed that the deceased persons used to drink the pump water from Broad Street, either constantly or occasionally…

The result of the inquiry, then, is, that there has been no particular outbreak or prevalence of cholera in this part of London except among the persons who were in the habit of drinking the water of the above-mentioned pump well.

I had an interview with the Board of Guardians of St James’s parish, on the evening of the 7th inst [September 7], and represented the above circumstances to them. In consequence of what I said, the handle of the pump was removed on the following day.”

— Dr. John Snow, letter to the Editor of the Medical Times and Gazette


Dr. William Thompson’s Report:

“I regret that my coauthors and I omitted statistically significant information in our 2004 article published in the journal Pediatrics. The omitted data suggested that African American males who received the MMR vaccine before age 36 months were at increased risk for autism.”

Dr. William Thompson, statement from his lawyer.


“I can’t believe we did what we did, but we did… The CDC knew about the relationship between the age of first MMR vaccine and autism incidence in African-American boys as early as 2003, but chose to cover it up…we’ve missed ten years of research because the CDC is so paralyzed right now by anything related to autism.”

Dr. William Thompson in a taped conversation with Dr. Brian Hooker

[1] Note to colleagues – if your name is not here, and it should be, send me a note, I will gladly add it.

Much of the information in this article on Dr. John Snow comes from this entry in Wikipedia.

You can directly support reformed vaccine safety research at The Institute for Pure and Applied Knowledge.

James Lyons-Weiler, PhD

Dr. Lyons-Weiler’s latest book, “Cures vs. Profits”, has just been released an is available via Amazon.com.  His book “Environmental and Genetic Causes of Autism” is due out in November, 2016.



Cures vs. Profits: Successes in Translational Research (World Scientific (323 pages). To help support the publicity campaign, click on the book cover, above!


SPOTLIGHT: Why Discussions of Vaccine Safety are Necessary and Good

RECENTLY I have seen an increasing trend in various places where informed individuals who are concerned over vaccine safety are chided for being “irresponsible” because we are “doing harm” by causing people to be unduly concerned over side effects from vaccines.

First, we who are concerned are not responsible for vaccine safety. That is Pharma and the CDC’s responsibility. They have abdicated that responsibility with misinformation, willfully denying health care  consumers the right to informed consent. We are expressing our concern over the “evidence” the CDC cites in support of their stated policies.

The CDC website, for example, is woefully black and white on the issue of the link between vaccines and autism/ASD.  Ok, let’s take their word for it.

How then do we explain the Special Master’s Court’s finding that vaccines have led to autism either directly, or indirectly, in some cases? Those conspiracy nuts.

How do we explain the numerous places where the FDA has communicated concerns over autism induced by vaccines, including requiring Pharma to mention such observations in their vaccine safety inserts? Why in the world would the FDA do that? They are doing people harm by saying such things!

How do we explain the hundreds of thousands of observations on late-onset, regressive autism made by parents?  There is no such thing as thousands of ‘anecdotes’.  Science begins with observations.

How do explain why CDC scientist and employee Dr. William Thompson felt the need to inform Brian Hooker, who was about to analyze data forced out the CDC under the Freedom of Information Act, that he knew that Hooker would find associations, and then proceed to describe, blow by blow, how other individuals at the CDC omitted results, and analyzed the data until initially found associations disappeared?

Please, let us place the responsibility where it lies: Pharma and the CDC has misled the American public to such a degree that individuals feel that questions and statements about vaccine adverse events – include the minority of total that occur that are reported in the VAERS – are doing harm?

I have some news: adverse events from vaccines include deaths, permanent loss of normal brain function, overnight demyelination of the CNS after the flu vaccine:

Sacheli A, Bauer R 2014. Influenza vaccine-induced CNS demyelination in a 50-year-old male. Am J Case Rep. 2014 Aug 31;15:368-73. doi: 10.12659/AJCR.891416.

Shoamanesh A, Traboulsee A. 2011. Acute disseminated encephalomyelitis following influenza vaccination. Vaccine. 29(46):8182-5. doi: 10.1016/j.vaccine.2011.08.103.

Did I do that damage? Am I even remotely responsible for these two case studies? No. I am also not responsible for why most Americans believe, incorrectly, that there is no way that vaccines can cause autism. That is because the CDC is not telling the entire story.

For autism/ASD, it’s the aluminum, and the mercury, and the process is immunoneuroexcitotoxicity. Because this situation can develop due to vaccination, the CDC had to fudge their studies to show no association. ( I should say that vaccination is not the only cause of microglia becoming stuck in their activated state. And autism/ASD is not the only condition that can result from this immune disorder).

Yes, childhood diseases can cause illness and in rare instances deaths.  And those deaths concern me, and, in my view, they should concern everyone. Such as the 10 who died from pertussis in California a few years ago. What exactly are the rates of of measles, mumps, or chickenpox deaths in the United States?  They are very, very low, in large part due to advances in medical care and to vaccinations.

Autism/ASD is now 1 in 48 – that’s more than 2% in the US.  Can we please have a rational discussion on how to prevent vaccine-induced immunoneuroexcitotoxicity? Could we maybe develop vaccines without aluminum? Could we please tell women who are pregnant that receiving a vaccine induces a strong immune response, including responses to fetal brain proteins? Is it OK if we let them know that these truths are science-based, so they can make up their own mind, without intimidation? Could we please expect that our doctors and nurses would know – in terms of percentages – what the risks are? More importantly, are we allowed to expect them to understand what those risks mean?

Let’s take measles as an example. There were about 0.15 deaths/1000 in 1900.

Take the theoretical worst-case scenario. If everyone in the US was unvaccinated, and lost all natural immunity, and measles swept the nation, that would be 54,000 deaths. That’s a lot. Way too many. But that was 1900. We now know how to control fever. (Never give Acetominophen after vaccination: it depletes glutathione, making microglial activation more likely).

Rates would be much lower. Let’s still be generous, and take 20,000 deaths due to measles. That’s still a lot.

Do I think we should get rid of the measles vaccine? No way.

But we now are looking at a future where 6,000,000 Americans will have vaccine-induced autism/ASD.

Which is worse? Can we have that discussion?

No, we cannot even do any type of analysis of whether the 6,000,000 cases of autism/ASD are “worth” the lives lost, and other costs due to the spread of the disease due to lack of vaccination by an informed public. That reality has been squelched.

But we don’t have to. How about we keep the measles vaccine, and all other vaccines, inform the public on the truth of the risks, and get to work developing newer, safer vaccines that do not include aluminum, or mercury, and that do not evoke a chronic stimulation of microglia.  We could use Virus-Like Particles (VLPs).  We could required single-dose packaging. Who wants microglia eating neuronal precursor cells (baby brain cells) and over-pruning dendrites?

We could also develop risk biomarkers to tell us which kids are most likely to develop autism from vaccines.

Oh, wait, that’s right. We can’t. Because everyone knows that vaccines do not cause autism.

Everyone, that is, except, of course, the FDA, the Special Master’s Court, and the hundreds of thousand of people who saw their children regress first-hand.

Vaccines are not handed down from God. They are man-made. We do not have to accept the risks of side effects and adverse events. We can expect better. The CDC ignores 20 years of research, funding by the NSF and the NIH (tax dollars) and cites their own studies, which they fudged, most of which the National Academy of Science/Institutes of medicine rejected in 2012 as being unsound science.

I think it is reasonable things for us to expect to discuss these topics without being afraid of being ridiculed, or shamed.  I think people should cut a wide swath before they chide others for being ridiculous for being concerned, because in their view, the benefit to society from vaccines is so great, and the risk of any adverse event so small. I doubt they have even looked at the statistics.

So, I ask them: how many cases of vaccine-induced autism/ASD from vaccines are too many?

Their reply? “There is no link between autism and vaccines“.

They are so misinformed, no rational discussion is even possible.

Vaccines can, indeed cause autism. The risk are cumulative, over a lifetime, not over the mere two weeks that doctors are told consider an adverse event. I will debate anyone, anywhere on this topic, as long as they read “Vaccine Whistleblower: Exposing Autism Research Fraud at the CDC“, and “Thimerosal: Let the Science Speak”  first. I’ve read Paul Offit’s book. This article was my response.

Instead of rational discourse, we see banal, grade-school like behavior. Bullying. Insults. And, in the case of genetics, blaming the victim.

Instead of a reasoned consideration of the fact, we learn of (some) doctors refusing to treat people who are no up-to-date on their vaccines. What ever happened to the Hippocratic oath?

Instead, we hear of family members getting angry with those who have decided to exercise their right of choice.

Objectivity is key in any consideration of public health policy. As long at the CDC continue to mislead the American public to think that vaccines are perfectly safe, the discussion must continue. The more they continue their disinformation campaign, the less the necessary research gets done.

We need to identify biomarkers of autism risk from vaccines.  We can’t expect such studies. Why? Vaccines do not cause autism, so why fund such studies?

We need to do clinical studies on treatments that will tone down aluminum-induced chronic microglial cell over-activation. Such studies will not be funded. Why bother? Aluminum, according to some, is not even a serious neurotoxin. 

We need newer, safer vaccines. Why? Aluminum is a neurotoxin. .

And we need to cancel CDC’s vaccine safety research contract. Why? Because they have, and continue to mislead the public, because they omitted results and fudged the results in numerous studies. They have done more than abdicate their responsibility to inform and protect us. They have prevented all of the safety research that should have been going on over the last 15 years. We need to wrench the responsibility of vaccine safety research away from them, and we need to do it NOW, before they fudge any more studies. What else are they lying to us about?

To me, the CDC and Pharma are grossly negligent. Picking up on Mary Holland’s analogy, who in her December 11 2015 article in The Jurist  likened the issue of discussing vaccine safety to someone yelling “Gunfire!” in a crowded movie theater… don’t blame me. Blame the gunman. He’s the one pulling the trigger.

December 15, 2015

See Mary Holland’s Academic Commentary in The Jurist: Legally Censoring Speech on Vaccines and Autism: A Response


Read: You Can Help Bring Major Reform to Vaccine Safety Research


New Book Released 2016 – Cures vs. Profits: Successes in Translational Research (World Scientific (323 pages). To help support the publicity campaign, click on the book cover, above!

How the CDC has Promoted Ignorance about Vaccine Safety

 CDCI HAVE BEEN READING widely both the primary literature and policy statements on vaccine safety from US Government Agencies as part of  the routine, due diligence required of objective scientist. It’s also par for the course for writing informative books. I would hate to think that I missed an important reference or source in any of my books. So I read on…

I have traced the ubiquitous “knowledge” that “vaccines do not cause autism” to the types of statements made by the US CDC. Perhaps in their quest to be clear, in their zeal to protect the population from contagious diseases, or perhaps because they have financial interests, the CDC loves to use black & white, unqualified statements.

Let’s look at three statements from the CDC website:

“Vaccines do not cause autism”

“There is no link between vaccines and autism.”

“Vaccine ingredients do not cause autism.”

The issue with these statement are that they are unqualified – meaning that they do not contain any qualifiers. Universal statements such as “never” and “always” are extremely rare in science and biomedicine.  We tend to hedge, using terms like “some”, and “may”, and “sometimes”, and for good reason. It’s the exceptions that count.

I am about to share with you information – certainly not new here, just ignored widely – that proves that these unqualified statements are wrong, misleading, and contribute to widespread ignorance on vaccine safety.

(1) The Special Masters court has found, and has made awards for damages, on repeated instances that vaccines have lead to neurological injuries that the Court has, in some cases, recognized as “autism”.  Two especially clear cases are Bailey Banks, who the court decided developed ADEM, leading to PPD-NOS (a type of autism), leading to an award of over $800,000, and Hanah Poling, whose family awarded $1.5 million for vaccine-induced autism. Other cases of vaccine induced neurological injuries leading to award include Eric Lassiter (diagnosed with autism), Elias Tembenis (PDD-NOS ), and Ryan Mojabi (diagnosed with autism, asthma and encephalopathy) and Richelle Oxley (encephalopathy).

(2) The CDC cites many studies that add to the conclusion that ‘vaccines do not cause autism’.

However, a 2012 National Academy of Science/Institutes of Medicine
report rejected 17/22 studies cited by the CDC as “flawed”.

The CDC continues to cite these studies, standing by them, and the policies upon which they are based, as if the National Academy of Sciences does not exist.

One of the studies was identified as a product of scientific fraud
by CDC Whistleblower Dr. William Thompson, who also pointed to numerous other studies were data were over-cooked. I’ve read the papers. Yes, they are over-cooked. See “Vaccine Whistleblower, Skyhorse Publishing ” for the full transcripts. They are jaw-dropping

The fact that the CDC continues to make unqualified statements, misleading the public, show their contempt of the Special Master’s Court position on these cases, reveals willful use of misstatements designed to misinform the public. As a result, the CDC can be considered liable for injuries caused by vaccines that could have been prevented if they did not mislead the public. Perhaps individuals would have taken a different path. Perhaps research would have moved forward to make vaccines safer.

(3) When the CDC is not involved , the scientific and biomedical research is clear: at least one mechanism by which autism can be caused by vaccines has been established: macrophages pick up neurotoxins (such as mercury and aluminum) and deposit them in organs, including the brain. There, these toxins can act,  in some people, to cause hyperactivation of microglial cells.

These cells usually clean up cellular debris, and act to  prune weak dendrites. When hyperactivated, they tend to go after any dendrites, over-pruning, leading to hypoconnectivity.  This causes the release of cytokines, leading to cell death apoptosis. Cytokines cause microglial cells to remain in the hyperctivated state, and a positive feedback loop is established. The immediate result is inflammation and encephalopathy. Importantly, this mechanism does not necessarily involve the recruitment of peripheral immune cells. The long-term effect are major developmental issues, in a variety of regions in the brain.

And the effects can vary from person to person. People with mutations in genes that encode protein involved in the cell’s normal detoxification pathways may suffer more severe damage (due to slower clearance).

The peer-reviewed published evidence for this mechanism will be reviewed & presented, with citations, in my book, “Genetic and Environmental Causes of Autism”.

We scientists have a responsibility to inform the public. I take that responsibility seriously. People who repeat unqualified claims such as those made by the CDC are spreading misinformation.

The important question is: how can we tell who will likely suffer this

To begin with, we know that families with one autistic member are likely to have a second. That is, the risk of autism is higher for new babies born to autistic families. This implies a genetic risk. The CDC and the FDA should be saying that vaccines are  contraindicated both for people with autism, and for people with siblings who have autism.

Also, many genes are being found that contribute to autism risk. An era of research in identifying biomarkers that can predict adverse neurological reactions to vaccines is  needed, and it was needed ten years ago. Because the CDC is misleading the American public, no such initiative is deemed necessary. This must change.

The first step is for the CDC to add qualifiers to their public statements, such as “may” and “in some people”. Perhaps:

“Vaccines have been shown to induce autism in some people”, or

“Vaccines may cause autism in some people”

are accurate, factual statements, backed by science, and backed by the US legal system.

Help bring the truth out. Please see this initiative and donate today!

Dec 6, 2015


New Books Released 2016 – Cures vs. Profits: Successes in Translational Research (World Scientific (323 pages).

The Environmental and Genetic Causes of AutismThe Environmental and Genetic Causes of Autism (Skyhorse Publishing)


You Can Help Bring Major Reform to Vaccine Safety Research

IF YOU HAVE been paying attention to the vaccine safety research controversies, you will know the following names:

Dr. Brian Hooker

Dr. William Thompson

Dr. Frank DeStefano

You may even know the names Dr. Coleen Boyle, and Dr. Julie Gerberding – and you will know the role that Senator Bill Posey (R, FL) has played.

You will know what Skyhorse Publishing is, and why the books they publish are vital to the very foundation of science in America.

If you don’t know anything about these issues – about how Bill Thompson disclosed research fraud at the CDC, involving key studies that the CDC still cites as evidence of no link between autism and vaccine – and about how these revelations have been confirmed by independent scrutiny of the publications involved – and about how former CDC Director Julie Gerberding left the CDC to work for Merck after overseeing the CDC during the period of time when the fraudulent research was alleged to have occurred, browse around my blog a while, or read the Chapter on Vaccines in Cures vs. Profits, or better yet get Kevin Barry’s book.

If you DO know about these issues, then you may not know what you can do to help bring about true reform in vaccine safety research.

Skyhorse Publishing has donated 40 copies each of “Thimerosal: Let the Science Speak” and “Vaccine Whistleblower: Exposing Autism Research Fraud at the CDC”  to the Institute for Pure and Applied Knowledge (IPAK, ipaknowledge.org). IPAK is sending one copy of each book, along with a Statement of Concern, to the Editors or Editors-in-Chief of 40 peer-reviewed journals in which those involved in the shady vaccine safety research practices have published.  We have the books, and the Statements of Concern printed, and ready to go. Here’s the countdown:


17 of 40 packages sent as of December 4, 2015.

IPAK is a registered 501(c)3 pure public charity. No one working in IPAK is allowed to have any financial interest in the research we conduct. Your donation will allow IPAK to send the next package.  This is an extremely important event in the history of vaccine research, and you can help turn the tide.  Our efforts do not stop at sending letters and packages. IPAK seeks to reform vaccine research to bring about objective, transparent, and, most importantly, peer-accountable practices for vaccine safety & efficacy studies. One of the most disturbing revelations by Bill Thompson was that the research teams at the CDC would change the study design, and the approach to analysis, without oversight by an Institutional Review Board (IRB) until they found a way to make associations between vaccination and autism appear to be non-significant. When they could not dissolve the associations they found via over-analysis, they simply left results out.


Visit ipaknowledge.org and donate for this special IPAK Issue Focus Fundraiser. Your donation is tax-deductible. Then also please accept my invitation to consider joining The Society for Pure and Applied Knowledge.  There is much work to do. Let’s go!

James Lyons-Weiler, PhD

Allison Park, PA


Paging Dr. Offit! Your Aluminum Neurotoxicity Reading Assignments Are Ready

AS COLLEGE PROFESSORS, my colleagues and I have always enjoyed the enthusiastic students who are eager to learn more. Those who stand out in myREADING memory are those who have requested more reading material. I have taught basic introductory biology, genetics, bioinformatics, courses in high-dimensional genomic and proteomic data analysis, and courses in study design and research ethics – and I always loved the gleam in the eye of students who just want to know.

Paging Dr. Offit!

Dr. Paul Offit earned millions of dollars from the sale of his patent for the Rotavirus vaccine after he voted to have it included in the pediatric vaccine schedule. He also appears to not be familiar with the body of peer-reviewed literature that condemns aluminum as a serious neurotoxin with well-characterized mechanisms of neurological damage.

In his book, “Deadly Choices: How the Anti-Vaccine Movement Threatens Us All” (Basic Books, New York), Offit is irresponsibly and recklessly dismissive of aluminum as a serious threat to the health of nearly all people by falsely reporting that:

“aluminum has been found to be harmful in only two groups of people: severely premature infants who receive large quantities of aluminum in intravenous fluids, and people on chronic dialysis (for kidney failure) who receive large quantities of aluminum in antacids”.

People absorb around very little of the aluminum they eat, but they absorb 100% of the aluminum injected in to their blood stream. [GENEROUSLY OFFERED CORRECTION/DETAILS: From Vaccine Papers, Al absorption from food is about 0.3%, typically within a range of 0.1-1%]. Offit claims, without citation, that aluminum in very quickly cleared from the body. He cites “researchers” (without citations) who studied aluminum concentrations in “blood” before and after receipt of aluminum-containing vaccines, and reports “No difference”.

Offit’s book was published in 2011. Unfortunately, it is evident that Offit did not even bother to search of the Pubmed, a wonderful public scientific research literature database at the National Center for Biotechnology Information, the standard resource for researchers who desire to know the latest on research topics in medicine, biology, psychiatry, and many other disciplines. A search reveals over 200 studies or papers on aluminum neurotoxicity before 2011. At the time of this writing (Nov. 2015), there are 393 studies or papers on the neurotoxicity of aluminum.

Some of these studies include direct discussions on the risk of aluminum in adjuvants in vaccines and provide data that demonstrate how aluminum works as a neurotoxin. Others discuss ways to alleviate neurotoxicity of aluminum. Others describe aluminum as a well-known neurotoxin responsible as a causal agent for neurodegenerative diseases.

Surely Offit, an expert placed on the National Vaccine Advisory Committee, the body in HHS responsible for making decisions on changes to the pediatric vaccine schedule, would have bothered to check the literature prior to 2011 while writing his book? If he had, he would have found studies with some compelling titles. The abstracts, and the papers themselves, are damning evidence for the use of aluminum as a vaccine adjuvant.

Here are some titles of the studies available at the time of his book-writing that individuals who are serious about vaccine safety might be interested in. Dr. Offit, for your convenience, I have included the links directly to the Pubmed entry:

Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction.” (2009)

Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.” (2009)

Aluminum-induced defective mitochondrial metabolism perturbs cytoskeletal dynamics in human astrocytoma cells.“(2009)

Role of metal ions in the abeta oligomerization in Alzheimer’s disease and in other neurological disorders.” (2008)

Aluminum adjuvant linked to Gulf War illness induces motor neuron death in mice.” (2007)

Neurological adverse events of immunization: experience with an aluminum adjuvanted meningococcal B outer membrane vesicle vaccine.” (2007)

Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer’s disease.” (2007)

Inflammation, neurodegenerative diseases, and environmental exposures.” (2004)

Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain.” (2004)

Neurotoxic effects of aluminium among foundry workers and Alzheimer’s disease.” (2004)

Neurological adverse events associated with vaccination.” (2002)

“The potential role of aluminium in Alzheimer’s disease.” (2002)

Just in case Dr. Offit is still involved in vaccine research, development or policy, and since he makes statements that appear in news articles on vaccine safety, I have taken the time to create a second reading list of more recent articles as well that Dr. Offit can add to his first reading list. Medical doctors really should keep abreast of new developments in medical research to stay professionally accredited.

But first, I have a hypothesis to share, which is indicated by past studies of numerous types. It came to me during my research for my forthcoming book, “Genetic and Environmental Causes of Autism”.

Is Macrophagic myofasciitis (MMF) Vaccine-Related Adult-Onset Autism/ASD?
A study in 2001 – a full decade before Offit’s book – reported central nervous system ailments eerily similar to those found in autism in patients diagnosed with macrophagic myofasciitis, symptomatic demyelinating CNS disorder, hemisensory or sensorimotor symptoms, bilateral pyramidal signs, cerebellar signs, visual loss, cognitive and behavioural disorders, and bladder dysfunction, supratentorial white matter hyperintense signals and corpus callosum atrophy (Authier et al., 2001).

Clinical features of MMF as described by Rigolet et al., (2014) are also strongly reminiscent of autism, including marked cognitive deficits (not related to pain, fatigue, or depression) including dysexecutive syndrome and visual memory impairment, and some cognitive deficits can appear unusually severe. Cognitive dysfunction was found to be stable over time. They also report that “classical therapeutic approaches are usually unsatisfactory making patient care difficult”.

Autism also involves cognitive deficits, executive function issues, memory impairment, and can involve severe cognitive deficits that are recalcitrant to treatment.

Additional Findings Support the Hypothesis

Mice injected with aluminum adjuvant doses equivalent to those given to US military service personnel showed both neuroinflammation and cell loss in the spinal cord and motor cortex, with consequent memory deficits (Petrik et al., 2007).

The cause of MMF has since been identified aluminum hydroxide from vaccines lesions (Gherardi et al., 2001; Authier et al., 2006; Gherardi et al., 2012; Rigolet M et al., 2014). Patients with MMF have an unusually long reaction at the site of injection of aluminum-containing vaccines in their muscle, and biospies show infiltration of muscle tissue by macrophages.

Here is chilling description of the effect of aluminum when used as an adjuvant:

“…poorly biodegradable aluminum-coated particles injected into muscle are promptly phagocytosed in muscle and the draining lymph nodes, and can disseminate within phagocytic cells throughout the body and slowly accumulate in the brain” (Gherardi et al., 2015).

This is important: microglial cells are macrophages with dual roles in the brain: they perform routine surveillance and clean-up of cellular debris, viruses and bacteria. Upon infection, or serious brain damage, however, they become activated, change shape, and go on the attack. Microglial overactivation is a leading candidate for increased apoptosis and neurological damage associated with autism.

The neurotoxic effects of aluminum salts are also apparent: it increases levels of glial activation, inflammatory cytokines and amyloid precursor protein within the brain (Bondy, 2010). Amyloid precursor protein is one of the main culprits for Alzheimer’s disease.

The medical community and the public should revisit the issue of whether aluminum is a necessary adjuvant for vaccines. Evidently, for some vaccines that use virus-like particles as opposed to attenuated or live virus vaccines, no adjuvant is needed.

Reading List #2

Here is the rest of Dr. Offit’s reading list of studies and papers published after 2010:

Trace elements in scalp hair samples from patients with relapsing-remitting multiple sclerosis.” (2015)

Correlation of aluminum and manganese concentration in scalp hair samples of patients having neurological disorders.” (2015)

Aluminum-induced entropy in biological systems: implications for neurological disease.” (2014)

Are there negative CNS impacts of aluminum adjuvants used in vaccines and immunotherapy?” (2014)

A sudden onset of a pseudo-neurological syndrome after HPV-16/18 AS04-adjuvated vaccine: might it be an autoimmune/inflammatory syndrome induced by adjuvants (ASIA) presenting as a somatoform disorder?” (2014)

Elevated brain aluminium and early onset Alzheimer’s disease in an individual occupationally exposed to aluminium: a case report.” (2014)

Prolonged exposure to low levels of aluminum leads to changes associated with brain aging and neurodegeneration.” (2014)

Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes.” (2013)

Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity.” (2013)

Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA syndrome) in commercial sheep.” (2013)

How aluminum, an intracellular ROS generator promotes hepatic and neurological diseases: the metabolic tale.” (2013)

Aluminum toxicity and astrocyte dysfunction: a metabolic link to neurological disorders.” (2011)

Aluminum vaccine adjuvants: are they safe?” (2011)

Metal ions affecting the neurological system.” (2011)

To be clear, Dr. Offit’s book could not include the references from the second reading list, as his book was published in 2011. But in the page and a half he takes to uses to claim that aluminum is only a problem for people with kidney failure and premature infants is terribly misleading, and is now also woefully out of date. As he and his profit-driven colleagues saw fit to allow vaccinations in babies between the age of 1 day to 2 years, it is of little reassurance that he knew that aluminum was harmful to premature babies.

Perhaps Dr. Offit was also not aware that the WHO Vaccine Safety Advisory Committee had, long before 2011, reported that there may be a subset of predisposed individuals who may be sensitive to aluminum-containing adjuvant (Authier et al., 2001).

Published scientific knowledge does not appear to play a role in the formation of vaccination policy in the United States.

November 16, 2015 (updated 11:22 AM)

Dr. James Lyons-Weiler is author of “Ebola: An Evolving Story” and “Cures vs. Profits: Successes in Translational Research“. He is also President, CEO and Chairman of the Board of the Institute for Pure and Applied Knowledge (IPAK).  IPAK is a pure public charity dedicated to providing impartial interpretation of research results without the influence of profit pressures. You can support IPAK with donations via the web. Your generous support will help Dr. Lyons-Weiler and his colleagues continue their efforts to keep the public, including Dr. Offit, informed.

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Authier FJ et al., 2001. Central nervous system disease in patients with macrophagic myofasciitis. Brain. 124(Pt 5):974-83.

Authier FJ, et al. 2006. AlOH3-adjuvanted vaccine-induced macrophagic myofasciitis in rats is influenced by the genetic background. Neuromuscul Disord 16(5):347–52.10.1016/j.nmd.2006.02.004

Bondy SC. 2010. The neurotoxicity of environmental aluminum is still an issue. Neurotoxicology. 31(5):575-81. doi: 10.1016/j.neuro.2010.05.009.

Gherardi RK, et al. 2001. Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. Brain 124(Pt 9):1821–31.10.1093/brain/124.9.1821

Gherardi RK et al., 2001. Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. Brain. 124(Pt 9):1821-31.

Gherardi R and Authier FJ. 2012. Macrophagic myofasciitis: characterization and pathophysiology. Lupus 21(2):184–9.10.1177/0961203311429557

Gherardi RK et al., 2015. Biopersistence and brain translocation of aluminum adjuvants of vaccines. Front Neurol. 2015 Feb 5;6:4. doi: 10.3389/fneur.2015.00004. eCollection 2015.

Petrik MS et al., 2007. Aluminum adjuvant linked to Gulf War illness induces motor neuron death in mice. Neuromolecular Med 9:83–100.

Rigolet M et al., 2014. Clinical features in patients with long-lasting macrophagic myofasciitis. Front Neurol. 5:230. doi: 10.3389/fneur.2014.00230. eCollection 2014.


New Books Released 2016

Cures vs. Profits: Successes in Translational Research (World Scientific (323 pages).

The Environmental and Genetic Causes of Autism (Skyhorse Publishing)



Books and Publications by James Lyons-Weiler


Getting A Feel for Authoring

Recently had the pleasure of going over the galleys of “Ebola”, and nearly 3/4 of the ways done with “Cures”, I’m getting to experience some of the perks of the life of an author.  For some reason, people open up to authors more, and want to share more ideas (which of course, I love).  I think part of it is that during the process of writing “Ebola”, I became a much better listener.   I had years of experience listening to investigators discuss their research plans, but I had a particular vested interest in those discussions: I wanted to effect the outcome of their research, and was trying to sell them my collaboration as a service.   I think being an author tells people that you’re interested in the human condition.

As an author, I’m finding that people from all walks of life open up to me, and really want to share all of their thoughts about a particular topic.  And I’ve found that I’m getting very good at bridging political, ideological and religious barriers.   There is something about the status of being an author on a scientific topic that causes most – emphasis on “most” – to afford one a tad more credibility.  I emphasize “most” because the reverse is true among experts in biodefense: they want me to prove that I have sufficient knowledge before they will brook a conversation!  Hopefully thus far I have not dissatisfied too many.

People from all walks of life know a lot more about some fairly complex issues than most in the biomedical field give them credit for.  They are aware of the issues – and they want to share their own understanding.  That’s why I think “Cures” will be very well received.  There are plenty of myths, and rumors about the evils of biomedicine – but there are just as many truths that are worth learning about.  Not all of the truths are pretty, but many are.  So in “Cures”, I’m focusing on finding the ever-elusive silver linings in tough topics like ADHD overdiagnosis.  It’s all too easy to sit on a rocking chair on my figurative front porch and complain to Gracie, or my neighbor, who sometimes comes over for iced tea, about how bad it is, and end the conversation with “Well, whaddya gonna do about it”?

The fact is, writing on these topics is empowering for me.  I have found a particular niche, and a particular combination of writing style that people say they like.  I mix the scientific literature with citations from the media – and quotes from experts – get all the peer-reviewed research results I can, and, using the combined powers of logic and passion for ending human pain and suffering, strive for a conversational, non-condescending tone, and somehow it comes out… interesting and informative.

People constantly ask me what my next book project will be, and right now, with “Cures”, when I describe the content, every person I have discussed it with has affirmed that they have heard that doctors don’t want cures, they want treatments, because treatments make them money.  Talk about taking a bull by the horns!  ADHD overdiagnosis and overtreatment, grapefruit and blood pressure, fecal microbiota transplants, mammograms, with an eye on history, and evolutionary biology, all open topics with plenty of confumantission among the public given discordant results from studies.  A contemplative, meditative, thorough treatment of the topics with the goal of identifying the positives… well it’s hard work, but it’s rewarding in its own right.  I’m learning a lot, too, which of course makes me happy.  The work will no doubt not be the last word on these complex topics, but I hope that my effort will help others understand what is known, what is not known, what is fact, and what is myth, when they hear that doctors don’t want to help patients with cures.  (Hint on the bottom line: there are attributes that tend to common to successful translational research studies, so motives be damned, I get to call out the good guys AND the bad guys – and I celebrate the good ones more than dwell on the bad).

If you’re an author, feel free to share w/me your transformative experiences as the world reacted to your “author” personality as opposed to your “scholar” personality.