Review of Peter Hotez’ Cruel – and Highly Unethical – Book

I don’t have a copy of Peter Hotez’ forthcoming book, but I have a snippet:

“There’s not only no link between vaccines and autism, there’s no plausibility…We’ve learned so much about the neurobiology of autism in the last few years. It can show that the changes in the brains of kids on the autism spectrum are beginning prenatally in the prefrontal cortex and temporal lobe, before the baby’s born, well before they ever see vaccine.”

From this alone, we can see Hotez’ book has some serious problems.

(1) These “changes”… maybe he means “differences”… I am very familiar with these studies, they did not study vaccines at all… thus,  these “changes” beginning pre-natally could be biomarkers for vaccine risk for ASD.  One simply cannot rule out causal factors unless one actually includes them in a study.

Dr. Hotez, like Dr. Francis Collins, appears to think they can divine knowledge without the appropriate study.

The study that is needed to rule out vaccines cannot be an observational study (correlation does not equal causation, remember?) but should instead have two arms:

Children w/early differences, vaccinated


Children w/early differences, unvaccinated

The way we know things and figure stuff out in science, is, well, to do science.

The IRB should be prepared to terminate the trial if when the neurodevelopmental disorders kick in for the vaccinated group, but not for the unvaccinated.

(2) The prefrontal cortex and the temporal lobe are not the only parts of the brain involved autism (for much greater detail see “The Environmental and Genetic Causes of Autism“;

(3) “…well before they ever see a vaccine”… well, if their mothers did not take doc’s advice and accept the thimerosal-containing flu vaccine, or refused the TdaP vaccine, neither of which is approved by the FDA for use on pregnant women, maybe…  but if their mothers were vaccinated during pregnancy, we know that maternal immune activation is not good for neurodevelopment.

We already know there is a genetic predisposition in ASD… but the question is, to what?  The science I’ve read tells me it’s a predisposition to ER Stress from vaccine metals.

There is far too much evidence that metals in vaccines can combine with mutational risk to create ER Hyperstress.  You can read all about that in

Autism is an Acquired Cellular Detoxification Deficiency Syndrome with Heterogeneous Genetic Predisposition  (publisher’s copyedit version, still being corrected)

As far as Dr. Hotez’ book, I am looking forward to reviewing all of the medical and genetic evidence he will bring forward to be able to say that vaccines did not cause autism in one person.  N=1.  One.  Sample size, 1.  I will also be expecting the full IRB documentation revealed for made available for this case study.

He should have known better.  He co-author is a bioethicist, after all.  Arthur Caplan, from NYU.  Here is Arthur Caplan telling everyone at a conference that they are at WAR with vaccine risk aware parents, and while he admits that one can never say positively that vaccines do not cause autism, in his words “You’ve got to fight unfair”.


Is this book another example of “fighting unfair”?

It is certainly cruel of these two professionals to deny that for some people, vaccines may cause autism.   They know the correct studies have not been conducted.  They know the lengths to which CDC has gone to make associations go away.   What they don’t know is how many people’s lives are adversely affected by vaccines.

A fast-growing number of professionals are calling for an end to the use of aluminum in vaccines [See LINKLINKLINKLINKLINK] in part because no dose escalation studies were conducted by the FDA in which they injected vaccine-relevant amounts of aluminum into infant mice and rats.  Newer studies are finding issues.

Instead of accurately portraying the state of knowledge, they choose to “Fight Unfair” because they HAVE to fight unfair – the science is swaying FAR AWAY from their position.

So much so that Nature just published a series of articles – they mention vaccines as a contributing causal factor to autoimmunity.

When I came to this issue while writing “Cures vs. Profits”, I promised myself above all else I would remain objective.  I promised to myself that while I was looking to celebrate the best of biomedicine, if I found issues, I would not shy away.  They may need to “Fight Unfair”.  We don’t.  We just share the science, as it comes out, putting together the pieces of the causality puzzle.  Science isn’t a fight.  Science is for asking questions.  Science is a way of knowing.  Science is an exploration into understanding.

Hotez, P. and A. Caplan. 2018. Vaccines Did Not Cause Rachel’s Autism: My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad John’s Hopkins University Press.



    1. Dr. James Lyons-Weiler provided an actual quote and a correctly scathing analysis of its contents. It is absolutely critical to call out Dr. Hotez on that quote, btw, because statements like his are used to support draconian vaccine “mandates” which undermine expression of basic human rights.

    2. If there is this much wrong with a snippet Hotez selected as his go-to point for the press, I can only imagine the number of non-sequitur and overdrawn conclusions the book must contain. LOL indeed.

      1. I know it is hard for you to comprehend this but 90% of what is in your book are studies proven not valid. The whole chapter on what the CDC ignored is all studies proven invalid and not credible. Dr Hotez loves his child and values her existence and knows she is not damaged. He knows that all the valid and credible science demonstrates vaccines do not cause autism. What could be more ethical than that?

      2. LOL proven by whom? Anonymous bloggists? Please. Show me where CDC gave ANY consideration to the studies including those that show biological plausibility for mitochondrial damage from thimerosal and aluminum, for ER stress from aluminum, for the association studies that DID find association. Anonymous bloggists have never, and will never, PROVE anything. They are 1–% irrelevant. Science marches on.

      3. You can’t prove CDC or ACIP did consider those studies in your book and you cannot prove they didn’t.

        How is the fundraising going? Raise enough funds to pay your taxes?

  1. “Vaccines are safe and effective “, then why has the tax payer paid out over 3 billion dollars for vaccine injuries?
    The autism tsunami is about to hit us and we still refuse to look at vaccines? No thing is off the table when the problem is this big.

    1. Vaccines are far safer the VPDs. We have paid ou 5400 claims and given out 5 billion vaccines, in the US in the last 30 years. That makes risk of vaccine injury literally 0.000011%. Measles risk of injury is 30% and there’s no compensation fund. That’s why we vax, because the benefits vastly outweigh the risks.

      1. The 30% chance of injury from measles is a lie. Like everything else you write.

        You probably mean temporary elevations of liver enzymes seen in some cases.

        An example of fighting unfair?

      2. vaccinesworkblog, You know full well that not all vaccine injury cases make it to the NVICP and that is takes years to get a ruling. Your assessment of measles injury is not relevant for Western societies with sanitation and modern medicine. I hope all readers see your comment and realize how blatantly you are trying to manipulate their perception. Readers who want more information should read Wayne Rhode’s book “Vaccine Court” –

      3. You know, you are perfectly capable of going to my about page and seeing my actual name. I am not a narcissist who names her blog after herself but I do put my name in my about.

        As for number of injury cases that make it to VICP, I would say that my experience and knowledge about the process is that most injury cases which go to VICP are not actually vaccine injuries and are denied compensation. VAERS states that most all reports of severe side effects are proven NOT connected to vaccines when medical evidence is analyzed. Therefore, most actual severe vaccine injuries DO make it to VICP and are compensated.

        As for Wayne Rhode, he has a child with autism so his book must be about how he feels, despite mountains of scientific evidence, that his child is vaccine injury. I pity the poor child.

      4. Fighting unfair again?

        Diarrhea is the most common “injury” listed in your link. You compare this to vaccine injuries that kill or disable people for life.

      5. That is absolute bullshit. A collaborative study between the DHHS and Harvard revealed the vaccine adverse events are underreported by a ratio of 100 to 1.
        Mortality is one factor. But then there is the skyrocketing neurodevelopmental and autoimmune diseases that vaccines can and do cause, according to the manufacturers.
        You want to stop vaccine hesitancy? Repeal the NVICP legislation and bring liability back to the pharmaceutical industry. This will incentivize them to do actual safety testing with double blind placebo trials with a genuine inert placebo and also do vaccinated v unvaccinated studies.
        People like you are anti science with your lies and spurious statistics.
        But you are losing. And I love it.

  2. A better estimate is from 1996-1998 in Romania – 21/32915 = 0.000638 = 0.638 deaths /1000. Now compare that the death rates from vaccines. Can’t? Won’t? Deny that measles or MMR vaccines don’t kill anyone? Or maybe VAERS is unreliable. Either way, you can’t say the benefit is there in terms of mortality. Stop making stuff up.

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